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RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Pathological tissue remodeling such as fibrosis is developed in various cardiac diseases. As one of cardiac activated-myofibroblast protein markers, CKAP4 may be involved in this process and the mechanisms have not been explored.Methods: We ...
Hong Zhu   +7 more
doaj   +3 more sources

Data of protein-RNA binding sites

open access: yesData in Brief, 2017
Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA ...
Wook Lee   +3 more
doaj   +3 more sources

PredPRBA: Prediction of Protein-RNA Binding Affinity Using Gradient Boosted Regression Trees

open access: yesFrontiers in Genetics, 2019
Protein-RNA interactions play essential roles in many biological aspects. Quantifying the binding affinity of protein-RNA complexes is helpful to the understanding of protein-RNA recognition mechanisms and identification of strong binding partners.
Lei Deng, Lei Deng, Wenyi Yang, Hui Liu
doaj   +3 more sources

An in vitro technique to identify the RNA binding-site sequences for RNA-binding proteins [PDF]

open access: yesBioTechniques, 2017
RNA–protein interactions play a major role in gene regulation. Although many techniques to analyze RNA–protein interactions have been developed, noteworthy challenges such as determining the RNA sequences that bind RNA-binding proteins (RBPs) remain ...
SunKyung Choi   +3 more
doaj   +3 more sources

The role of disorder in RNA binding affinity and specificity [PDF]

open access: yesOpen Biology, 2020
Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
doaj   +1 more source

The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?

open access: yesFrontiers in Oncology, 2021
The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li   +6 more
doaj   +1 more source

RNA-binding proteins [PDF]

open access: yesWormBook, 2006
The C. elegans genome encodes many RNA-binding proteins (RBPs) with diverse functions in development, indicative of extensive layers of post-transcriptional control of RNA metabolism. A number of C. elegans RBPs have been identified by forward or reverse genetics. They tend to display tissue-specific mutant phenotypes, which underscore their functional
Lee, Min'Ho, Schedl, Tim
openaire   +3 more sources

Research progress of RNA binding motif protein family-mediated alternative splicing in cardiomyopathy [PDF]

open access: yesJichu yixue yu linchuang, 2022
RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif.
LIU Shu, DING Hong, ZHAO Ke-xin, BAI Feng, ZHANG Xiao-wei
doaj   +1 more source

Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP

open access: yesGenome Biology, 2022
Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale.
Klara Kuret   +4 more
doaj   +1 more source

RNA binding proteins in osteoarthritis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder. Its progression is characterized by aberrant expression of genes involved in inflammation, proliferation, and metabolism of chondrocytes ...
Qian Yi   +9 more
openaire   +3 more sources

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