Results 21 to 30 of about 1,861,609 (310)
Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism [PDF]
, 2013 Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe.
Bottcher, B. +4 more
core +1 more source
Microbiology Spectrum, 2022 Proteomic profiling of RNA-binding proteins in Leishmania is currently limited to polyadenylated mRNA-binding proteins, leaving proteins that interact with nonadenylated RNAs, including noncoding RNAs and pre-mRNAs, unidentified.
Karunakaran Kalesh +5 more
doaj +1 more source
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation. [PDF]
, 2013 The initiation of protein synthesis plays an essential regulatory role in human biology. At the center of the initiation pathway, the 13-subunit eukaryotic translation initiation factor 3 (eIF3) controls access of other initiation factors and mRNA to the
Arias-Palomo, Ernesto +6 more
core +1 more source
Chloroplast RNA-binding proteins [PDF]
Current Genetics, 2003 Chloroplast gene expression is regulated by nucleus-encoded factors, which mainly act at the post-transcriptional level. Plastid RNA-binding proteins (RBPs) represent good candidates for mediating these functions. The picture emerging from recent analyses is that of a great number of differentially regulated RBPs, which are organized in distinct ...
openaire +2 more sources
Helical defects in microRNA influence protein binding by TAR RNA binding protein.
PLoS ONE, 2015 BackgroundMicroRNAs (miRNAs) are critical post-transcriptional regulators of gene expression. Their precursors have a globally A-form helical geometry, which prevents most proteins from identifying their nucleotide sequence.
Roderico Acevedo +3 more
doaj +1 more source
Technology in Cancer Research & Treatment, 2020 RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS +4 more
doaj +1 more source
Saturation mutagenesis reveals manifold determinants of exon definition. [PDF]
, 2017 To illuminate the extent and roles of exonic sequences in the splicing of human RNA transcripts, we conducted saturation mutagenesis of a 51-nt internal exon in a three-exon minigene.
Anquetil, Vincent +9 more
core +2 more sources
RNA‐binding properties of hnRNP proteins [PDF]
European Journal of Biochemistry, 1988 The RNA‐binding properties of the hnRNP monoparticle proteins were examined using a renaturing blotting procedure. All ‘core’ proteins are able to bind single‐stranded nucleic acids, probably not sequence‐specific. The core proteins C1 and, in one case A2 and B2, are able to bind nucleic acids which are double‐stranded or which show a high degree of ...
Schenkel, J. +3 more
openaire +3 more sources
Effective RNA Regulation by Combination of Multiple Programmable RNA-Binding Proteins
Applied Sciences, 2020 RNAs play important roles in gene expression through translation and RNA splicing. Regulation of specific RNAs is useful to understand and manipulate specific transcripts.
Misaki Sugimoto +3 more
doaj +1 more source
Nature Communications, 2023 Viral RNA-host protein interactions are indispensable during RNA virus transcription and replication, but their detailed structural and dynamical features remain largely elusive. Here, we characterize the binding interface for the SARS-CoV-2 stem-loop 3 (
Dong Zhang +7 more
doaj +1 more source