Results 31 to 40 of about 7,392,133 (313)
Computational and Structural Biotechnology Journal, 2021 The interactions among non-coding RNA (ncRNA) and RNA binding protein (RBP) are increasingly recognized as one of basic mechanisms in gene regulation, and play a crucial role in cancer progressions.
Leiming Jiang +4 more
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Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
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Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba [PDF]
, 2010 Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly ...
Petrovic-Stojanovska, Biljana +5 more
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PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif [PDF]
, 2011 PAPD5 is one of the seven members of the family of noncanonical poly(A) polymerases in human cells. PAPD5 was shown to polyadenylate aberrant pre-ribosomal RNAs in vivo, similar to degradation-mediating polyadenylation by the noncanonical poly(A ...
Bilen, B. +7 more
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Characterization of post-transcriptional regulatory network of RNA-binding proteins using computational predictions and deep sequencing data [PDF]
, 2013 This report is divided into three parts: Data Analysis, Mathematical Modeling and Conclusion and future directions. In the Data Analysis part, various methods and tools for characterizing the post-transcriptional regulatory networks of RNA-binding ...
Mohsen, Khorshid
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Targeting RNA binding protein in prostate cancer
Molecular & Cellular Oncology, 2017 RNA binding protein (RBP) controls multiple aspects of RNA metabolism and plays crucial roles in many physiopathological contexts, including cancer. We recently identified an RBP HNRNPL as a novel prostate cancer dependency via regulation of RNA splicing,
Teng Fei
doaj +1 more source
Protein interactions in Xenopus germ plasm RNP particles [PDF]
, 2013 Hermes is an RNA-binding protein that we have previously reported to be found in the ribonucleoprotein (RNP) particles of Xenopus germ plasm, where it is associated with various RNAs, including that encoding the germ line determinant Nanos1.
Nijjar, Sarbjit +6 more
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Research Progress in RNA-Binding Proteins
International Journal of Molecular Sciences, 2022 RNA-binding proteins are everywhere and accompany RNA molecules at every stage of their molecular life, from “birth” (transcription) through “growing up” (maturation), “active life” (molecular function) until “death” (turnover) [...]
openaire +2 more sources
RNA-Binding Proteins in Acute Leukemias [PDF]
International Journal of Molecular Sciences, 2020 Acute leukemias are genetic diseases caused by translocations or mutations, which dysregulate hematopoiesis towards malignant transformation. However, the molecular mode of action is highly versatile and ranges from direct transcriptional to post-transcriptional control, which includes RNA-binding proteins (RBPs) as crucial regulators of cell fate ...
Konstantin Schuschel +5 more
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Non-Coding RNA, 2023 Circular RNAs (circRNAs), a newly recognized group of noncoding RNA transcripts, have established widespread attention due to their regulatory role in cell signaling. They are covalently closed noncoding RNAs that form a loop, and are typically generated
Yuka Ikeda +8 more
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