RNA-binding proteins in bacteria [PDF]
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions.
Erik Holmqvist, Jörg Vogel
openaire +5 more sources
Molecular principles underlying dual RNA specificity in the Drosophila SNF protein [PDF]
The first RNA recognition motif of the Drosophila SNF protein is an example of an RNA binding protein with multi-specificity. It binds different RNA hairpin loops in spliceosomal U1 or U2 small nuclear RNAs, and only in the latter case requires the ...
DeKoster, Gregory T +4 more
core +3 more sources
Possible Involvement of the Phloem Lectin in Long-Distance Viroid Movement
Incubation with cucumber phloem exudate in vitro results in a dramatic decrease in the electrophoretic mobility of Hop stunt viroid. UV cross-linking and a combination of size exclusion and ion exchange chromatography indicate that this phenomenon ...
R. A. Owens, M. Blackburn, B. Ding
doaj +1 more source
Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts. [PDF]
Cellular protein-RNA complexes assemble on nascent transcripts, but methods to observe transcription and protein binding in real time and at physiological concentrations are not available.
Duss, Olivier +5 more
core +2 more sources
Crimean-Congo hemorrhagic fever virus nucleocapsid protein has dual RNA binding modes. [PDF]
Crimean Congo hemorrhagic fever, a zoonotic viral disease, has high mortality rate in humans. There is currently no vaccine for Crimean Congo hemorrhagic fever virus (CCHFV) and chemical interventions are limited.
Subbiah Jeeva +4 more
doaj +1 more source
RNA binding proteins in osteoarthritis
Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder. Its progression is characterized by aberrant expression of genes involved in inflammation, proliferation, and metabolism of chondrocytes ...
Qian Yi +9 more
openaire +3 more sources
Mechanism of RNA recognition by a Musashi RNA-binding protein
The Musashi RNA-binding proteins (RBPs) regulate translation of target mRNAs and maintenance of cell stemness and tumorigenesis. Musashi-1 (MSI1), long considered as an intestinal and neural stem cell marker, has been more recently found to be over ...
Jinan Wang +4 more
doaj +1 more source
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
PredPRBA: Prediction of Protein-RNA Binding Affinity Using Gradient Boosted Regression Trees
Protein-RNA interactions play essential roles in many biological aspects. Quantifying the binding affinity of protein-RNA complexes is helpful to the understanding of protein-RNA recognition mechanisms and identification of strong binding partners.
Lei Deng, Lei Deng, Wenyi Yang, Hui Liu
doaj +1 more source
Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis [PDF]
Metabolic control of gene expression coordinates the levels of specific gene products to meet cellular demand for their activities. This control can be exerted by metabolites acting as regulatory signals and/or a class of metabolic enzymes with dual ...
Bohne, Alexandra-Viola +6 more
core +8 more sources

