Results 11 to 20 of about 3,111,959 (339)
Cell, 2018 Proteins such as FUS phase separate to form liquid-like condensates that can harden into less dynamic structures. However, how these properties emerge from the collective interactions of many amino acids remains largely unknown.
Jie Wang +13 more
semanticscholar +3 more sources
A large-scale binding and functional map of human RNA-binding proteins
Nature, 2020 Many proteins regulate the expression of genes by binding to specific regions encoded in the genome1. Here we introduce a new data set of RNA elements in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the ...
Eric L. Van Nostrand +37 more
semanticscholar +3 more sources
A census of human RNA-binding proteins
Nature Reviews Genetics, 2014 S. Gerstberger, M. Hafner, T. Tuschl
semanticscholar +3 more sources
RNA-binding proteins: modular design for efficient function
Nature Reviews Molecular Cell Biology, 2007 B. M. Lunde, C. Moore, G. Varani
semanticscholar +3 more sources
RNA buffers the phase separation behavior of prion-like RNA binding proteins
Science, 2018 Shovamayee Maharana +16 more
semanticscholar +3 more sources
RNA-binding proteins in human genetic disease
Nature Reviews Genetics, 2020 F. Gebauer +3 more
semanticscholar +3 more sources
Context-dependent control of alternative splicing by RNA-binding proteins
Nature Reviews Genetics, 2014 Xiang-Dong Fu, M. Ares
semanticscholar +3 more sources
The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation
eLife, 2021 TDP-43 is a nuclear RNA-binding protein that forms neuronal cytoplasmic inclusions in two major neurodegenerative diseases, ALS and FTLD. While the self-assembly of TDP-43 by its structured N-terminal and intrinsically disordered C-terminal domains has ...
Juan Carlos Rengifo-Gonzalez +8 more
doaj +1 more source
Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis [PDF]
, 2013 Metabolic control of gene expression coordinates the levels of specific gene products to meet cellular demand for their activities. This control can be exerted by metabolites acting as regulatory signals and/or a class of metabolic enzymes with dual ...
Bohne, Alexandra-Viola +6 more
core +8 more sources
Frontiers in Molecular Neuroscience, 2021 Core spliceosome and related RNA-binding proteins aggregate in Alzheimer’s disease (AD) brain even in early asymptomatic stages (AsymAD) of disease.
Qi Guo +15 more
doaj +1 more source