Results 41 to 50 of about 2,650,407 (299)
Systematic discovery of Xist RNA binding proteins
Cell, 2015 Summary Noncoding RNAs (ncRNAs) function with associated proteins to effect complex structural and regulatory outcomes. To reveal the composition and dynamics of specific noncoding RNA- protein complexes (RNPs) in vivo, we developed comprehensive ...
Ci Chu +9 more
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mBio, 2022 Excessive inflammation can cause tissue damage and autoimmunity, sometimes accompanied by severe morbidity or mortality. Numerous negative feedback mechanisms exist to prevent unchecked inflammation, but this restraint may come at the cost of suboptimal ...
Giraldina Trevejo-Nuñez +6 more
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Plant RNA binding proteins for control of RNA virus infection
Frontiers in Physiology, 2013 Plant RNA viruses have effective strategies to infect host plants through either direct or indirect interactions with various host proteins, thus suppressing the host immune system.
Sung Un eHuh, Kyung-Hee ePaek
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It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation
Nature Structural & Molecular Biology, 2021 Biomolecular condensates that form via phase separation are increasingly regarded as coordinators of cellular reactions that regulate a wide variety of biological phenomena.
Hannah J. Wiedner, Jimena Giudice
semanticscholar +1 more source
Guardian of Genetic Messenger-RNA-Binding Proteins
Biomolecules, 2016 RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express
Antje Anji, Meena Kumari
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Protein solubility and folding enhancement by interaction with RNA. [PDF]
PLoS ONE, 2008 While basic mechanisms of several major molecular chaperones are well understood, this machinery has been known to be involved in folding of only limited number of proteins inside the cells. Here, we report a chaperone type of protein folding facilitated
Seong Il Choi +12 more
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Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
eLife, 2023 Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016).
Liang Ma, Jasleen Singh, Randy Schekman
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Chloroplast RNA-binding proteins [PDF]
Current Genetics, 2003 Chloroplast gene expression is regulated by nucleus-encoded factors, which mainly act at the post-transcriptional level. Plastid RNA-binding proteins (RBPs) represent good candidates for mediating these functions. The picture emerging from recent analyses is that of a great number of differentially regulated RBPs, which are organized in distinct ...
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Research Progress in RNA-Binding Proteins
International Journal of Molecular Sciences, 2022 RNA-binding proteins are everywhere and accompany RNA molecules at every stage of their molecular life, from “birth” (transcription) through “growing up” (maturation), “active life” (molecular function) until “death” (turnover) [...]
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RNA-Binding Proteins in Acute Leukemias [PDF]
International Journal of Molecular Sciences, 2020 Acute leukemias are genetic diseases caused by translocations or mutations, which dysregulate hematopoiesis towards malignant transformation. However, the molecular mode of action is highly versatile and ranges from direct transcriptional to post-transcriptional control, which includes RNA-binding proteins (RBPs) as crucial regulators of cell fate ...
Konstantin Schuschel +5 more
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