Results 1 to 10 of about 1,182,184 (311)

RNA binding proteins in osteoarthritis

Frontiers in Cell and Developmental Biology, 2022
Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder.
Qian Yi, Qian Yi, Qian Yi, Zhenhan Deng, Jiaji Yue, Jinglong He, Jianyi Xiong, Wei Sun, Weichao Sun, Weichao Sun   +9 more
doaj   +3 more sources

RNA-Binding Proteins in Dinoflagellates. [PDF]

Int J Mol Sci
The described features of dinoflagellate gene expression indicate the predominance of post-transcriptional and translational regulation over transcriptional control. These microorganisms also exhibit extensive RNA editing and distinctive splicing characteristics.
Berdieva M, Safonov P, Skarlato S.
europepmc   +3 more sources

RNA-binding proteins in bacteria [PDF]

Nature Reviews Microbiology, 2018
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions.
Erik Holmqvist, Jörg Vogel, Holmqvist Erik   +2 more
exaly   +4 more sources

RNA-Binding Proteins in Cardiomyopathies

Journal of Cardiovascular Development and Disease
The post-transcriptional regulation of gene expression plays an important role in heart development and disease. Cardiac-specific alternative splicing, mediated by RNA-binding proteins, orchestrates the isoform switching of proteins that are essential ...
De-Li Shi
doaj   +4 more sources

Survey of the binding preferences of RNA-binding proteins to RNA editing events

Genome Biology, 2022
Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular activities.
Xiaolin Hu, Qin Zou, Li Yao, Xuerui Yang
doaj   +3 more sources

An in vitro technique to identify the RNA binding-site sequences for RNA-binding proteins [PDF]

BioTechniques, 2017
RNA–protein interactions play a major role in gene regulation. Although many techniques to analyze RNA–protein interactions have been developed, noteworthy challenges such as determining the RNA sequences that bind RNA-binding proteins (RBPs) remain ...
SunKyung Choi, Chungoo Park, Kyoon Eon Kim, Kee K. Kim   +3 more
doaj   +3 more sources

Editorial: RNA binding proteins in neuroscience

Frontiers in Molecular Neuroscience, 2023
Anca F. Savulescu, Epaminondas Doxakis
doaj   +3 more sources

Regulation of RNA-binding proteins by small biomolecules [PDF]

Nature Reviews Molecular Cell Biology
Weili Miao, Vanessa Lopez-Pajares, Paul A Khavari   +2 more
exaly   +2 more sources

RNA‐PROTACs: Degraders of RNA‐Binding Proteins [PDF]

Angewandte Chemie International Edition, 2020
AbstractDefects in the functions of RNA binding proteins (RBPs) are at the origin of many diseases; however, targeting RBPs with conventional drugs has proven difficult. PROTACs are a new class of drugs that mediate selective degradation of a target protein through a cell's ubiquitination machinery.
Alice Ghidini, Antoine Cléry, François Halloy, Frédéric H. T. Allain, Jonathan Hall   +4 more
openaire   +6 more sources

The role of disorder in RNA binding affinity and specificity [PDF]

Open Biology, 2020
Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
doaj   +1 more source