Results 31 to 40 of about 3,122,867 (388)

Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer’s Disease

open access: yesFrontiers in Molecular Neuroscience, 2021
Core spliceosome and related RNA-binding proteins aggregate in Alzheimer’s disease (AD) brain even in early asymptomatic stages (AsymAD) of disease.
Qi Guo   +15 more
doaj   +1 more source

RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles

open access: yesNature Plants, 2021
Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal pathogens and silence fungal virulence-related genes through a phenomenon called ‘cross-kingdom RNAi’. It remains unknown, however, how sRNAs are selectively loaded
Baoye He   +8 more
semanticscholar   +1 more source

Classifying RNA-binding proteins based on electrostatic properties. [PDF]

open access: yesPLoS Computational Biology, 2008
Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
doaj   +1 more source

Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions

open access: yesbioRxiv, 2022
Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation, especially at low endogenous concentrations found in cells, are thought ...
Mrityunjoy Kar   +12 more
semanticscholar   +1 more source

RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific

open access: yesScientific Reports, 2023
Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack known RNA-binding domains (RBDs).
Debashish Ray   +17 more
doaj   +1 more source

How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms.

open access: yesMolecules and Cells, 2020
RNA-binding proteins (RBPs) comprise a large class of over 2,000 proteins that interact with transcripts in all manner of RNA-driven processes. The structures and mechanisms that RBPs use to bind and regulate RNA are incredibly diverse.
M. Corley, Margaret C Burns, Gene W. Yeo
semanticscholar   +1 more source

Survey of the binding preferences of RNA-binding proteins to RNA editing events

open access: yesGenome Biology, 2022
Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular activities.
Xiaolin Hu, Qin Zou, Li Yao, Xuerui Yang
doaj   +1 more source

The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?

open access: yesFrontiers in Oncology, 2021
The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li   +6 more
doaj   +1 more source

RNA-binding Proteins in Regulating mRNA Stability and Translation: Roles and Mechanisms in Cancer.

open access: yesSeminars in Cancer Biology, 2022
RNA-binding proteins (RBPs) are key players in cellular physiology through posttranscriptional regulation of the expression of target RNA transcripts.
Wei Li, Xiaolan Deng, Jianjun Chen
semanticscholar   +1 more source

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