A cytoplasmic complex mediates specific mRNA recognition and localization in yeast [PDF]
In eukaryotes, hundreds of mRNAs are localized by specialized transport complexes. For localization, transcripts are recognized by RNA-binding proteins and incorporated into motor-containing messenger ribonucleoprotein particles (mRNPs).
Henning Urlaub +41 more
core +2 more sources
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
AU-rich RNA binding proteins in hematopoiesis and leukemogenesis
Posttranscriptional mechanisms are now widely acknowledged to play a central role in orchestrating gene-regulatory networks in hematopoietic cell growth, differentiation, and tumorigenesis.
Baou, M. +5 more
core +1 more source
Protein interactions in Xenopus germ plasm RNP particles [PDF]
Hermes is an RNA-binding protein that we have previously reported to be found in the ribonucleoprotein (RNP) particles of Xenopus germ plasm, where it is associated with various RNAs, including that encoding the germ line determinant Nanos1.
Nijjar, Sarbjit +6 more
core +2 more sources
Guardian of Genetic Messenger-RNA-Binding Proteins
RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express
Antje Anji, Meena Kumari
doaj +1 more source
RNA-Binding Proteins in Cardiomyopathies
The post-transcriptional regulation of gene expression plays an important role in heart development and disease. Cardiac-specific alternative splicing, mediated by RNA-binding proteins, orchestrates the isoform switching of proteins that are essential ...
De-Li Shi
doaj +1 more source
Characterisation of Bombyx mori odorant-binding proteins reveals that a general odorant-binding protein discriminates between sex pheromone components [PDF]
In many insect species, odorant-binding proteins (OBPs) are thought to be responsible for the transport of pheromones and other semiochemicals across the sensillum lymph to the olfactory receptors (ORs) within the antennal sensilla.
Field, L.M. +23 more
core +1 more source
Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA. [PDF]
P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that the proteins are essential and are involved in ribosome biogenesis.
Martin Ciganda, Noreen Williams
doaj +1 more source
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016).
Liang Ma, Jasleen Singh, Randy Schekman
doaj +1 more source
Single molecule probing of disordered RNA binding proteins
Summary: Liquid-liquid phase separation of intrinsically disordered proteins is known to underlie diverse pathologies such as neurodegeneration, cancer, and aging.
Kevin Rhine, Sua Myong
doaj +1 more source

