Results 51 to 60 of about 3,122,867 (388)

The 54-kD Protein of Signal Recognition Particle Contains a Methionine-rich RNA Binding Domain [PDF]

open access: yes, 1990
Signal recognition particle (SRP) plays the key role in targeting secretory proteins to the membrane of the endoplasmic reticulum (Walter, P., and V. R. Lingappa. 1986. Annu. Rev. CeliBiol. 2:499-516). It consists of SRP7S RNA and six proteins. The 54-kD
Dobberstein, Bernhard   +4 more
core   +1 more source

Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules

open access: yesBiomolecules, 2020
Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
doaj   +1 more source

Plant RNA binding proteins for control of RNA virus infection

open access: yesFrontiers in Physiology, 2013
Plant RNA viruses have effective strategies to infect host plants through either direct or indirect interactions with various host proteins, thus suppressing the host immune system.
Sung Un eHuh, Kyung-Hee ePaek
doaj   +1 more source

Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins [PDF]

open access: yes, 2018
The HIV-1 nucleocapsid (NC) protein represents an excellent molecular target for the development of antiretrovirals by virtue of its well-characterized chaperone activities, which play pivotal roles in essential steps of the viral life cycle. Our ongoing
Caliendo, Giuseppe   +16 more
core   +2 more sources

Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response

open access: yesmBio, 2022
Excessive inflammation can cause tissue damage and autoimmunity, sometimes accompanied by severe morbidity or mortality. Numerous negative feedback mechanisms exist to prevent unchecked inflammation, but this restraint may come at the cost of suboptimal ...
Giraldina Trevejo-Nuñez   +6 more
doaj   +1 more source

Protein solubility and folding enhancement by interaction with RNA. [PDF]

open access: yesPLoS ONE, 2008
While basic mechanisms of several major molecular chaperones are well understood, this machinery has been known to be involved in folding of only limited number of proteins inside the cells. Here, we report a chaperone type of protein folding facilitated
Seong Il Choi   +12 more
doaj   +1 more source

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

open access: yes, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan   +17 more
core   +2 more sources

RNA‐binding properties of hnRNP proteins [PDF]

open access: yesEuropean Journal of Biochemistry, 1988
The RNA‐binding properties of the hnRNP monoparticle proteins were examined using a renaturing blotting procedure. All ‘core’ proteins are able to bind single‐stranded nucleic acids, probably not sequence‐specific. The core proteins C1 and, in one case A2 and B2, are able to bind nucleic acids which are double‐stranded or which show a high degree of ...
Schenkel, J.   +3 more
openaire   +3 more sources

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. [PDF]

open access: yes, 1994
To study the functions of heterogeneous nuclear ribonucleoproteins (hnRNPs), we have characterized nuclear polyadenylated RNA-binding (Nab) proteins from Saccharomyces cerevisiae.
Datar, KV   +4 more
core   +1 more source

Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA. [PDF]

open access: yesPLoS ONE, 2012
P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that the proteins are essential and are involved in ribosome biogenesis.
Martin Ciganda, Noreen Williams
doaj   +1 more source

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