Results 61 to 70 of about 3,122,867 (388)
A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome [PDF]
, 2013 This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Dunker, A. Keith +6 more
core +2 more sources
Pat1 RNA‐binding proteins: Multitasking shuttling proteins [PDF]
WIREs RNA, 2019 AbstractPost‐transcriptional regulation of gene expression is largely achieved at the level of splicing in the nucleus, and translation and mRNA decay in the cytosol. While the regulation may be global, through the direct inhibition of central factors, such as the spliceosome, translation initiation factors and mRNA decay enzymes, in many instances ...
Vindry, Caroline +2 more
openaire +3 more sources
FLASH: ultra-fast protocol to identify RNA-protein interactions in cells
, 2019 Determination of the in vivo binding sites of RNA-binding proteins (RBPs) is paramount to understanding their function and how they affect different aspects of gene regulation.
Akhtar, A. +4 more
core +1 more source
Serial interactome capture of the human cell nucleus [PDF]
, 2015 Novel RNA-guided cellular functions are paralleled by an increasing number of RNA-binding proteins (RBPs). Here we present ‘serial RNA interactome capture’ (serIC), a multiple purification procedure of ultraviolet-crosslinked poly(A)–RNA–protein ...
Albrecht, Anne-Susann +5 more
core +2 more sources
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
eLife, 2023 Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016).
Liang Ma, Jasleen Singh, Randy Schekman
doaj +1 more source
RNA-binding activity of the rat calmodulin-binding PEP-19 protein and of the long PEP-19 isoform [PDF]
, 2012 Synthesis of H1\u2da histone protein, in the developing rat brain, seems to be regulated mainly at the post-transcriptional level. Since regulation of RNA metabolism depends on a series of RNA-binding proteins, we have been searching for RNA-binding ...
DI LIEGRO, C. +6 more
core +1 more source
De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. [PDF]
, 2014 The splicing regulator Polypyrimidine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine element, allowing recognition of diverse pyrimidine-rich sequences.
Black, Douglas L +5 more
core +4 more sources
PLoS Biology, 2004 Genes encoding RNA-binding proteins are diverse and abundant in eukaryotic genomes. Although some have been shown to have roles in post-transcriptional regulation of the expression of specific genes, few of these proteins have been studied systematically.
André P. Gerber, D. Herschlag, P. Brown
semanticscholar +1 more source
Single molecule probing of disordered RNA binding proteins
STAR Protocols, 2022 Summary: Liquid-liquid phase separation of intrinsically disordered proteins is known to underlie diverse pathologies such as neurodegeneration, cancer, and aging.
Kevin Rhine, Sua Myong
doaj +1 more source
Nature Cell Biology, 2019 Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular secretion; however, the mechanisms underlying these processes remain unclear.
Andrew M. Leidal +16 more
semanticscholar +1 more source