Results 21 to 30 of about 1,151,716 (261)
RNA-binding proteins: TRAPping RNA bases [PDF]
Current Biology, 2000 In Bacillus subtilis, tryptophan biosynthesis is regulated by a mechanism called attenuation. The new crystal structure of the 'trp RNA binding attenuation protein', TRAP, in complex with RNA has provided new structural insights into how proteins can bind RNA to regulate transcription and translation.
Muto, Yutaka +2 more
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RNA‐binding properties of hnRNP proteins [PDF]
European Journal of Biochemistry, 1988 The RNA‐binding properties of the hnRNP monoparticle proteins were examined using a renaturing blotting procedure. All ‘core’ proteins are able to bind single‐stranded nucleic acids, probably not sequence‐specific. The core proteins C1 and, in one case A2 and B2, are able to bind nucleic acids which are double‐stranded or which show a high degree of ...
Schenkel, J. +3 more
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DNA and RNA Quadruplex-Binding Proteins [PDF]
International Journal of Molecular Sciences, 2014 Four-stranded DNA structures were structurally characterized in vitro by NMR, X-ray and Circular Dichroism spectroscopy in detail. Among the different types of quadruplexes (i-Motifs, minor groove quadruplexes, G-quadruplexes, etc.), the best described are G-quadruplexes which are featured by Hoogsteen base-paring.
Brazda, Vaclav +3 more
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Biomolecules, 2020 Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
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mBio, 2022 Excessive inflammation can cause tissue damage and autoimmunity, sometimes accompanied by severe morbidity or mortality. Numerous negative feedback mechanisms exist to prevent unchecked inflammation, but this restraint may come at the cost of suboptimal ...
Giraldina Trevejo-Nuñez +6 more
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Plant RNA binding proteins for control of RNA virus infection
Frontiers in Physiology, 2013 Plant RNA viruses have effective strategies to infect host plants through either direct or indirect interactions with various host proteins, thus suppressing the host immune system.
Sung Un eHuh, Kyung-Hee ePaek
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RNA circuits and RNA-binding proteins in T cells [PDF]
Trends in Immunology, 2023 RNA is integral to the regulatory circuits that control cell identity and behavior. Cis-regulatory elements in mRNAs interact with RNA-binding proteins (RBPs) that can alter RNA sequence, stability, and translation into protein. Similarly, long noncoding RNAs (lncRNAs) scaffold ribonucleoprotein complexes that mediate transcriptional and post ...
Wandi S. Zhu +2 more
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Guardian of Genetic Messenger-RNA-Binding Proteins
Biomolecules, 2016 RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express
Antje Anji, Meena Kumari
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Protein solubility and folding enhancement by interaction with RNA. [PDF]
PLoS ONE, 2008 While basic mechanisms of several major molecular chaperones are well understood, this machinery has been known to be involved in folding of only limited number of proteins inside the cells. Here, we report a chaperone type of protein folding facilitated
Seong Il Choi +12 more
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RNA‐binding proteins and RNA methylation in myeloid cells
Immunological Reviews, 2021 AbstractRNA‐binding proteins (RBPs) regulate all aspects of the life of mRNA transcripts. They are critically important in regulating immune responses, most notably by restraining excessive inflammation that can potentially lead to tissue damage.
Marian Bataclan +2 more
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