Results 21 to 30 of about 3,111,959 (339)
RNA-binding proteins contribute to small RNA loading in plant extracellular vesicles
Nature Plants, 2021 Plants use extracellular vesicles (EVs) to transport small RNAs (sRNAs) into their fungal pathogens and silence fungal virulence-related genes through a phenomenon called ‘cross-kingdom RNAi’. It remains unknown, however, how sRNAs are selectively loaded
Baoye He +8 more
semanticscholar +1 more source
Classifying RNA-binding proteins based on electrostatic properties. [PDF]
PLoS Computational Biology, 2008 Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
doaj +1 more source
bioRxiv, 2022 Macromolecular phase separation is thought to be one of the processes that drives the formation of membraneless biomolecular condensates in cells. The dynamics of phase separation, especially at low endogenous concentrations found in cells, are thought ...
Mrityunjoy Kar +12 more
semanticscholar +1 more source
RNA-binding proteins that lack canonical RNA-binding domains are rarely sequence-specific
Scientific Reports, 2023 Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack known RNA-binding domains (RBDs).
Debashish Ray +17 more
doaj +1 more source
How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms.
Molecules and Cells, 2020 RNA-binding proteins (RBPs) comprise a large class of over 2,000 proteins that interact with transcripts in all manner of RNA-driven processes. The structures and mechanisms that RBPs use to bind and regulate RNA are incredibly diverse.
M. Corley, Margaret C Burns, Gene W. Yeo
semanticscholar +1 more source
Survey of the binding preferences of RNA-binding proteins to RNA editing events
Genome Biology, 2022 Background Adenosine-to-inosine (A-to-I) editing is an important RNA posttranscriptional process related to a multitude of cellular and molecular activities.
Xiaolin Hu, Qin Zou, Li Yao, Xuerui Yang
doaj +1 more source
The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?
Frontiers in Oncology, 2021 The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li +6 more
doaj +1 more source
Robust single-cell discovery of RNA targets of RNA binding proteins and ribosomes
Nature Methods, 2021 RNA-binding proteins (RBPs) are critical regulators of gene expression and RNA processing that are required for gene function. Yet the dynamics of RBP regulation in single cells is unknown.
Kristopher W Brannan +10 more
semanticscholar +1 more source
Identification of RNA-binding Proteins
Bio-Protocol, 2016 This protocol describes the extraction of RNA-binding proteins (RBPs) from cell lysates. In order to pull down target RBPs, 5-bromo-UTP (BrUTP)-incorporated RNA probes are used, which are generated by in vitro transcription.
Kazuya Masuda, Tadamitsu Kishimoto
doaj +1 more source
PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs [PDF]
, 2018 A large number of RNA binding proteins (RBPs) and miRNAs bind to the 3′ untranslated regions of mRNA, but methods to dissect their function and interactions are lacking.
Chaudhari, Hemangi G +3 more
core +3 more sources