Results 51 to 60 of about 3,111,959 (339)
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
eLife, 2023 Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016).
Liang Ma, Jasleen Singh, Randy Schekman
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RNA-binding activity of the rat calmodulin-binding PEP-19 protein and of the long PEP-19 isoform [PDF]
, 2012 Synthesis of H1\u2da histone protein, in the developing rat brain, seems to be regulated mainly at the post-transcriptional level. Since regulation of RNA metabolism depends on a series of RNA-binding proteins, we have been searching for RNA-binding ...
DI LIEGRO, C. +6 more
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De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. [PDF]
, 2014 The splicing regulator Polypyrimidine Tract Binding Protein (PTBP1) has four RNA binding domains that each binds a short pyrimidine element, allowing recognition of diverse pyrimidine-rich sequences.
Black, Douglas L +5 more
core +4 more sources
PLoS Biology, 2004 Genes encoding RNA-binding proteins are diverse and abundant in eukaryotic genomes. Although some have been shown to have roles in post-transcriptional regulation of the expression of specific genes, few of these proteins have been studied systematically.
André P. Gerber, D. Herschlag, P. Brown
semanticscholar +1 more source
Single molecule probing of disordered RNA binding proteins
STAR Protocols, 2022 Summary: Liquid-liquid phase separation of intrinsically disordered proteins is known to underlie diverse pathologies such as neurodegeneration, cancer, and aging.
Kevin Rhine, Sua Myong
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GraphProt: modeling binding preferences of RNA-binding proteins [PDF]
, 2014 We present GraphProt, a computational framework for learning sequence- and structure-binding preferences of RNA-binding proteins (RBPs) from high-throughput experimental data.
Daniel Maticzka +3 more
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Nature Cell Biology, 2019 Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular secretion; however, the mechanisms underlying these processes remain unclear.
Andrew M. Leidal +16 more
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A global function for transcription factors in assisting RNA polymerase II termination. [PDF]
, 2017 The role of transcription factors (TFs) on nucleosome positioning, RNA polymerase recruitment, and transcription initiation has been extensively characterized.
Chanfreau, Guillaume F, Roy, Kevin
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Nature CommunicationsADP-ribosylation has long been recognised as a key regulator of essential signalling pathways, including the DNA damage response. However, only recent and ongoing technological advances are beginning to make it possible to investigate its distinct forms ...
Helen Dauben +6 more
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RNA-Binding Proteins: Splicing Factors and Disease
Biomolecules, 2015 Pre-mRNA splicing is mediated by interactions of the Core Spliceosome and an array of accessory RNA binding proteins with cis-sequence elements. Splicing is a major regulatory component in higher eukaryotes.
Alger M. Fredericks +3 more
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