Results 1 to 10 of about 348,149 (303)
Heliyon, 2023 Objective: Colorectal cancer remains a significant challenge with high mortality rates. The aim of this study was to investigate the effect of targeting the microRNA-148a/WNT10b axis with the long non-coding RNA LINC00261 on the proliferation and ...
Juanli Xi +4 more
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Frontiers in Bioengineering and Biotechnology, 2023 Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase +6 more
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Frontiers in Bioinformatics, 2022 The enzyme Dicer is a component of many small RNA (sRNA) pathways involved in RNA processing for post-transcriptional regulation, anti-viral response and control of transposable elements.
Ben Murcott +5 more
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Small Interfering RNA- Modern Approach for Intervening Pathological Conditions
NUST Journal of Natural Sciences, 2021 RNA interference (RNAi) refers to the inhibition of gene expression by small double-stranded RNA molecules. This technology can prove to be a breakthrough biological discovery of the decade as it has the potential to revolutionize the field of ...
Shazia Choudhary +7 more
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A small interfering RNA (siRNA) database for SARS-CoV-2
Scientific Reports, 2021 Coronavirus disease 2019 (COVID-19) rapidly transformed into a global pandemic, for which a demand for developing antivirals capable of targeting the SARS-CoV-2 RNA genome and blocking the activity of its genes has emerged.
Inácio Gomes Medeiros +5 more
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Small interfering RNA inhibition of Andes virus replication. [PDF]
PLoS ONE, 2014 Andes virus (ANDV) is the most common causative agent of hantavirus pulmonary syndrome (HPS) in the Americas, and is the only hantavirus associated with human-to-human transmission. Case fatality rates of ANDV-induced HPS are approximately 40%. There are
Cheng-Feng Chiang +3 more
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Potential Application of Small Interfering RNA in Gastro-Intestinal Tumors
Pharmaceuticals, 2022 Despite the progress made in the diagnoses and therapy of gastrointestinal cancers, these diseases are still plagued by a high mortality. Thus, novel therapeutic approaches are urgently required.
Pasquale Losurdo +10 more
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Small Interfering RNA in Colorectal Cancer Liver Metastasis Therapy
Technology in Cancer Research & Treatment, 2022 Colorectal cancer (CRC) is associated with numerous genetic disorders and cellular abnormalities, and liver metastasis is a common health concern in patients with CRC.
Junlin Xie MM, Shubin Wang MD
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Traffic into silence: endomembranes and post-transcriptional RNA silencing. [PDF]
, 2014 microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-
Chen, Xuemei +2 more
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Recent studies on non-coding small RNAs in plants
浙江大学学报. 农业与生命科学版, 2014 There are many non-coding small RNAs in plants and animals, which regulate gene expression via direct cleavage of target mRNAs or via inhibition of translation at the post-transcriptional level.
Shen Enhui +3 more
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