Results 1 to 10 of about 3,183,009 (298)

Virus-Mediated System for Simultaneous Gene Silencing and Genome Editing in Cotton [PDF]

Plants
Plant viral vectors are powerful tools for the transient expression of exogenous genes, enabling not only virus-induced gene silencing (VIGS) but also virus-induced genome editing (VIGE).
Yufeng Zheng, Lianjia Zhao, Yulin Tian, Jiahao Lin, Xiaodong Liu, Jianfeng Lei   +5 more
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The divergent V2 protein encoded by parsley yellow leaf curl virus is a suppressor of transcriptional and post-transcriptional gene silencing and a potential symptom determinant [PDF]

BMC Plant Biology
The Geminiviridae family encompasses over 500 species of economically important plant viruses. A new geminivirus species named parsley yellow leaf curl virus (PYLCV) was first identified in 2020 in Southeastern Iran.
Hasan Zeitooni, Laura Medina-Puche, Rosa Lozano-Durán, Masoud Shams-Bakhsh   +3 more
doaj   +2 more sources

Prior Biological Knowledge Improves Genomic Prediction of Growth-Related Traits in Arabidopsis thaliana

Frontiers in Genetics, 2021
Prediction of growth-related complex traits is highly important for crop breeding. Photosynthesis efficiency and biomass are direct indicators of overall plant performance and therefore even minor improvements in these traits can result in significant ...
Muhammad Farooq, Muhammad Farooq, Aalt D. J. van Dijk, Aalt D. J. van Dijk, Harm Nijveen, Mark G. M. Aarts, Willem Kruijer, Thu-Phuong Nguyen, Shahid Mansoor, Dick de Ridder   +9 more
doaj   +1 more source

Global Analysis of RNA-Dependent RNA Polymerase-Dependent Small RNAs Reveals New Substrates and Functions for These Proteins and SGS3 in Arabidopsis

Non-Coding RNA, 2021
RNA silencing pathways control eukaryotic gene expression transcriptionally or posttranscriptionally in a sequence-specific manner. In RNA silencing, the production of double-stranded RNA (dsRNA) gives rise to various classes of 20–24 nucleotide (nt ...
Xia Hua, Nathan D. Berkowitz, Matthew R. Willmann, Xiang Yu, Eric Lyons, Brian D. Gregory   +5 more
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Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development

Frontiers in Plant Science, 2021
Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism.
Ahmed H. El-Sappah, Ahmed H. El-Sappah, Ahmed H. El-Sappah, Kuan Yan, Kuan Yan, Qiulan Huang, Qiulan Huang, Qiulan Huang, Md. Monirul Islam, Quanzi Li, Quanzi Li, Yu Wang, Yu Wang, Muhammad Sarwar Khan, Xianming Zhao, Xianming Zhao, Reyazul Rouf Mir, Jia Li, Jia Li, Khaled A. El-Tarabily, Khaled A. El-Tarabily, Manzar Abbas, Manzar Abbas   +22 more
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Pygmy MicroRNA: Surveillance Cops in Therapy Kingdom

Molecular Medicine, 2016
MicroRNAs (miRNAs) are well preserved in every animal. These pygmy-sized (21–23 nt) noncoding RNAs scattered in the genome are responsible for micromanaging versatile gene regulation.
Utpal Bhadra, Pradipta Patra, Jagamohan Chhatai, Manika Pal-Bhadra   +3 more
doaj   +1 more source

RNA Interference: A Novel Technology for Virus Disease Management in Crop Plants

Madras Agricultural Journal, 2021
RNAs play a significant role in regulating gene expression and their principalareas have been exploited for the control of plant viruses by the discoveryof RNA silencing mechanism.
Karthikeyan Gandhi, Rajamanickam Suppaiah, Suganyadevi Murugesan, Nagendran Krishnan   +3 more
doaj   +1 more source

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

Cell Reports, 2016
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA.
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen   +17 more
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Identification and Characterization of miRNA Transcriptome in Asiatic Cotton (Gossypium arboreum) Using High Throughput Sequencing

Frontiers in Plant Science, 2017
MicroRNAs (miRNAs) are small 20–24nt molecules that have been well studied over the past decade due to their important regulatory roles in different cellular processes.
Muhammad Farooq, Shahid Mansoor, Shahid Mansoor, Hui Guo, Imran Amin, Peng W. Chee, M. Kamran Azim, Andrew H. Paterson   +7 more
doaj   +1 more source

Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

eLife, 2022
In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during ...
Sarah Lensch, Michael H Herschl, Connor H Ludwig, Joydeb Sinha, Michaela M Hinks, Adi Mukund, Taihei Fujimori, Lacramioara Bintu   +7 more
doaj   +1 more source