Results 11 to 20 of about 623,056 (302)

RNA-Mediated Gene Silencing Signals Are Not Graft Transmissible from the Rootstock to the Scion in Greenhouse-Grown Apple Plants Malus sp. [PDF]

, 2012
RNA silencing describes the sequence specific degradation of RNA targets. Silencing is a non-cell autonomous event that is graft transmissible in different plant species.
Bai, Ban, Broothaerts, Buhtz, Conny Tränkner, Crasweller, Dieter Treutter, Espley, Flachowsky, Flachowsky, Gilissen, Harada, Henryk Flachowsky, Hewezi, Himber, Iris Szankowski, Kalantidis, Kasai, Lespinasse, Li, Li, Lusser, Magda-Viola Hanke, Mallory, Martin, Melnyk, Palauqui, Sascha Waidmann, Schwab, Shaharuddin, Smith, Szankowski, Thilo C. Fischer, Tournier, Tränkner, Voinnet, Wassenegger, Yoo   +37 more
core   +3 more sources

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

Cell Reports, 2016
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA.
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen   +17 more
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M, Falk, Bryce W, Huang, Ting-Kuo, McDonald, Karen A   +3 more
core   +3 more sources

Identification and Characterization of miRNA Transcriptome in Asiatic Cotton (Gossypium arboreum) Using High Throughput Sequencing

Frontiers in Plant Science, 2017
MicroRNAs (miRNAs) are small 20–24nt molecules that have been well studied over the past decade due to their important regulatory roles in different cellular processes.
Muhammad Farooq, Shahid Mansoor, Shahid Mansoor, Hui Guo, Imran Amin, Peng W. Chee, M. Kamran Azim, Andrew H. Paterson   +7 more
doaj   +1 more source

Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling [PDF]

, 2008
In the plant pathogen Phytophthora infestans, nuclear integration of inf1 transgenic DNA sequences results in internuclear gene silencing of inf1. Although silencing is regulated at the transcriptional level, it also affects transcription from other ...
Appiah, A.A., Govers, F., Gow, N.A.R., Grenville-Briggs, L., Li, S., Shepherd, S.J., Walker, C.A., West, P., van   +7 more
core   +3 more sources

Potato spindle tuber viroid as Inducer of RNA Silencing in Infected Tomato

Molecular Plant-Microbe Interactions, 2001
Potato spindle tuber viroid (PSTVd), an RNA plant pathogen encoding no known proteins, induces systemic symptoms on tomato plants. We report detection of small RNAs of approximately 25 nucleotides with sequence specificity to PSTVd in infected plants: an
Asuka Itaya, Alexey Folimonov, Yoshie Matsuda, Richard S. Nelson, Biao Ding   +4 more
doaj   +1 more source

Factors influencing Barley Stripe Mosaic Virus-mediated gene silencing in wheat [PDF]

, 2010
Virus induced gene silencing (VIGS) is a technology that has been used primarily to target the virus genome in infected plants. However, if the virus genome carries inserts derived from the host plant, the system could be employed to target the mRNAs ...
Cakir, Cahid, Tör, Mahmut
core   +2 more sources

A Complex Network of MicroRNAs Expressed in Brain and Genes Associated with Amyotrophic Lateral Sclerosis

International Journal of Genomics, 2013
Amyotrophic Lateral Sclerosis (ALS) is a rare neurological disease affecting mainly motor neurons and often leads to paralysis and death in extreme cases.
Santosh Shinde, Neelima Arora, Utpal Bhadra   +2 more
doaj   +1 more source

Epigenetic silencing in transgenic plants

Frontiers in Plant Science, 2015
Epigenetic silencing is a natural phenomenon in which the expression of gene is regulated through modifications of DNA, RNA or histone proteins. It is a mechanism for defending host genomes against the effects of transposable element, viral infection and
Sarma eRajeev Kumar, Pushpanathan eAnunanthini, Sathishkumar eRamalingam   +2 more
doaj   +1 more source

Genomic prediction in plants: opportunities for ensemble machine learning based approaches [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2023
Background: Many studies have demonstrated the utility of machine learning (ML) methods for genomic prediction (GP) of various plant traits, but a clear rationale for choosing ML over conventionally used, often simpler parametric methods, is still ...
Aalt D.J. van Dijk, Shahid Mansoor, Muhammad Farooq, Dick de Ridder, Harm Nijveen   +4 more
doaj   +1 more source