Results 11 to 20 of about 452,517 (308)

Factors influencing Barley Stripe Mosaic Virus-mediated gene silencing in wheat [PDF]

, 2010
Virus induced gene silencing (VIGS) is a technology that has been used primarily to target the virus genome in infected plants. However, if the virus genome carries inserts derived from the host plant, the system could be employed to target the mRNAs ...
Cakir, Cahid, Tör, Mahmut, Cakir, C., Tör, M.   +3 more
core   +1 more source

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

Cell Reports, 2016
Ewing sarcoma cells depend on the EWS-FLI1 fusion transcription factor for cell survival. Using an assay of EWS-FLI1 activity and genome-wide RNAi screening, we have identified proteins required for the processing of the EWS-FLI1 pre-mRNA.
Patrick J. Grohar, Suntae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole K. Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Huppi, Magdalena Grandin, Kristen Gehlhaus, Carleen A. Klumpp-Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen   +17 more
doaj   +1 more source

Identification and Characterization of miRNA Transcriptome in Asiatic Cotton (Gossypium arboreum) Using High Throughput Sequencing

Frontiers in Plant Science, 2017
MicroRNAs (miRNAs) are small 20–24nt molecules that have been well studied over the past decade due to their important regulatory roles in different cellular processes.
Muhammad Farooq, Shahid Mansoor, Shahid Mansoor, Hui Guo, Imran Amin, Peng W. Chee, M. Kamran Azim, Andrew H. Paterson   +7 more
doaj   +1 more source

RNA-Mediated Gene Silencing Signals Are Not Graft Transmissible from the Rootstock to the Scion in Greenhouse-Grown Apple Plants Malus sp. [PDF]

, 2012
RNA silencing describes the sequence specific degradation of RNA targets. Silencing is a non-cell autonomous event that is graft transmissible in different plant species.
Hanke, Magda-Viola, Waidmann, Sascha, Tränkner, Conny, Fischer, Thilo C., Sascha Waidmann, Flachowsky, Henryk, Dieter Treutter, Treutter, Dieter, Iris Szankowski, Magda-viola Hanke, Szankowski, Iris, Henryk Flachowsky, Thilo C. Fischer, Conny Tränkner   +13 more
core   +1 more source

TRUE Gene Silencing

International Journal of Molecular Sciences, 2022
TRUE gene silencing is an RNA-mediated gene expression control technology and is termed after tRNase ZL-utilizing efficacious gene silencing. In this review, I overview the potentiality of small guide RNA (sgRNA) for TRUE gene silencing as novel therapeutics.
openaire   +2 more sources

Potato spindle tuber viroid as Inducer of RNA Silencing in Infected Tomato

Molecular Plant-Microbe Interactions, 2001
Potato spindle tuber viroid (PSTVd), an RNA plant pathogen encoding no known proteins, induces systemic symptoms on tomato plants. We report detection of small RNAs of approximately 25 nucleotides with sequence specificity to PSTVd in infected plants: an
Asuka Itaya, Alexey Folimonov, Yoshie Matsuda, Richard S. Nelson, Biao Ding   +4 more
doaj   +1 more source

Potato virus X-induced gene silencing in leaves and tubers of potato [PDF]

, 2004
Virus induced gene silencing (VIGS) is increasingly used to generate transient loss-of-function assays and has potential as a powerful reverse-genetics tool in functional genomic programs as a more rapid alternative to stable transformation. A previously
Loake, Gary J, Taylor, M, Gilroy, Eleanor M, Hrubikova, Katarina, Hein, I, Birch, Paul; id_orcid, Taylor, Mark, Hrubikova, K, Birch, P, Hein, Ingo; id_orcid, Millam, S, Faivre-Rampant, O, Faivre-Rampant, Odile, Lacomme, Christophe, Gilroy, E M, Millam, Steve, Lacomme, C, Loake, G J   +17 more
core   +1 more source

A Complex Network of MicroRNAs Expressed in Brain and Genes Associated with Amyotrophic Lateral Sclerosis

International Journal of Genomics, 2013
Amyotrophic Lateral Sclerosis (ALS) is a rare neurological disease affecting mainly motor neurons and often leads to paralysis and death in extreme cases.
Santosh Shinde, Neelima Arora, Utpal Bhadra   +2 more
doaj   +1 more source

Epigenetic silencing in transgenic plants

Frontiers in Plant Science, 2015
Epigenetic silencing is a natural phenomenon in which the expression of gene is regulated through modifications of DNA, RNA or histone proteins. It is a mechanism for defending host genomes against the effects of transposable element, viral infection and
Sarma eRajeev Kumar, Pushpanathan eAnunanthini, Sathishkumar eRamalingam   +2 more
doaj   +1 more source

Virus-induced gene silencing

浙江大学学报. 农业与生命科学版, 2008
The term virus-induced gene silencing' (VIGS) was first used to describe the phenomenon of recovery from virus infection, a natural plant antiviral mechanism, which recently has been exploited as a genetic technique involving recombinant viruses with a ...
XU You-ping, XU Qiu-fang, SONG Xiao-yi, ZHANG Zhi-xin, CAI Xin-zhong   +4 more
doaj   +1 more source