Results 1 to 10 of about 400,234 (218)
mSystems, 2020 Systemic and quantitative investigations of human plasma proteins (proteomics) and Staphylococcus aureus-specific antibodies (immunoproteomics) provide complementary information and hold promise for the discovery of biomarkers in Staphylococcus aureus ...
Stephan Michalik +7 more
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Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine
Metabolites, 2022 Metabolic fingerprinting by mass spectrometry aims at the comprehensive, semiquantitative analysis of metabolites. Isotope dilution, if successfully implemented, may provide a more reliable, relative quantification.
Fadi Fadil +6 more
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Genome-wide compendium and functional assessment of in vivo heart enhancers
Nature Communications, 2016 Identification of non-coding variants has outstripped our ability to annotate and interpret them. Dickel et al. present a compendium of over 80,000 putative human heart enhancers and demonstrate that two conserved enhancers are required for proper ...
Diane E. Dickel +20 more
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Association of lipid rafts cholesterol with clinical profile in fragile X syndrome
Scientific Reports, 2022 Fragile X syndrome (FXS) is the most prevalent monogenic cause of intellectual disability and autism spectrum disorder (ASD). Affected individuals have a high prevalence of hypocholesterolemia, however, the underlying mechanisms and the clinical ...
Amanda Toupin +7 more
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Frontiers in Plant Science, 2014 Endosperm transfer cells (ETC) are one of four main types of cells in endosperm. A characteristic feature of ETC is the presence of cell wall in-growths that create an enlarged plasma membrane surface area.
Sergiy eLopato +3 more
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UBB pseudogene 4 encodes functional ubiquitin variants
Nature Communications, 2020 Ubiquitin pseudogenes are present in many organisms but whether they encode functional proteins has remained unclear. Here, the authors show that human UBB pseudogene 4 produces ubiquitin variants with amino acid compositions and cellular functions that ...
Marie-Line Dubois +13 more
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Communications Biology, 2023 Uptake of obligate intracellular bacterial pathogens into mammalian epithelial cells is critically dependent on modulation of the host’s endocytic machinery.
Dominik Spona +3 more
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TIE-UP-SIN: A Method for Enhanced Identification of Protein–Protein Interactions
Bio-ProtocolProtein–protein interactions (PPIs) govern nearly all aspects of cellular physiology, yet identifying these interactions under native conditions remains challenging.
Maximilian Schedlowski +9 more
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Induction of central host signalling kinases during pneumococcal infection of human THP-1 cells
Frontiers in Cellular and Infection Microbiology, 2016 Streptococcus pneumoniae is a widespread colonizer of the mucosal epithelia of the upper respiratory tract of human. However, pneumococci are also responsible for numerous local as well as severe systemic infections, especially in children under the age ...
Thomas Peter Kohler +3 more
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Stem Cell Research, 2020 Floating-Harbor syndrome (FLHS) is a rare genetic disease caused by mutations in the SRCAP gene. Here, we generated an induced pluripotent stem cell line from gingival fibroblasts of a male patient with a heterozygous mutation in exon 34 of the SRCAP ...
M. Franz +7 more
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