Results 11 to 20 of about 3,788,624 (254)

Clinical Functional Genomics [PDF]

Cancers, 2021
Functional genomics is the study of how the genome and its products, including RNA and proteins, function and interact to affect different biological processes. The field of functional genomics includes transcriptomics, proteomics, metabolomics and epigenomics, as these all relate to controlling the genome leading to expression of particular phenotypes.
Seren Carpenter, R. Conlan
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Functional genomics in Spiralia

Briefings in Functional Genomics, 2023
Abstract Our understanding of the mechanisms that modulate gene expression in animals is strongly biased by studying a handful of model species that mainly belong to three groups: Insecta, Nematoda and Vertebrata. However, over half of the animal phyla belong to Spiralia, a morphologically and ecologically diverse animal clade with ...
Francisco M Martín-Zamora, Billie E Davies, Rory D Donnellan, Kero Guynes, José M Martín-Durán   +4 more
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REGIA, an EU project on functional genomics of transcription factors from Arabidopsis thaliana [PDF]

, 2002
Paz-Ares J, Valencia A, Costantino P, et al. REGIA, an EU project on functional genomics of transcription factors from Arabidopsis thaliana. Comparative and Functional Genomics.
H. P. Mock, COSTANTINO, Paolo, A. Valencia, C. Martin, B. Weisshaar, T. Laux, C. Gatz, Valencia, Alfonso, Ratcliff, Frank, M. Zabeau, Tonelli, Chiara, J. Traas, F. Parcy, T. Kavanagh, Paz Ares, Javier, P. Gilmartin, Somssich, Imre, H. Baumlein, Carbonero Zalduegui, Pilar, G. Coupland, Engström, Peter, Weisshaar, Bernd, Hans P. Mock, Dröege-Laser, Wolfgang, The REGIA Consortium, Hordsworth, Mike, B. Davies, F. Ratcliff, I. Somssich, Coupland, George, P. Vittorioso, Laux, Thomas, L. Colombo, Reindl, Andreas, Javier Paz-Ares, S. Smeekens, Sablowski, Robert, J. Giraudat, Kavanagh, Tony, S. Kushnir, Gatz, Christiane, Parcy, François, Zabeau, Marc, R. Sablowski, Javier Paz Ares, C. Tonelli, M. Hordsworth, W. Droege Laser, Smeekens, Sjef, Giraudat, Jerome, Mock, Hans Peter, Colombo, Lucia, Baumlein, Helmut, Angenent, Cerco C., Ruberti, Ida, Kushnir, Sergei, Davies, Brendan, P. Costantino, P. Carbonero, Martin, Cathie, VITTORIOSO, Paola, Traas, Jan, Gilmartin, Phil, J. Paz Ares, P. Engstrom, A. Reindl, G. C. Angenent, I. Ruberti, Engström, The REGIA Consortium, Peter,, Angenent, G.C., Carbonero, P., Paz-Ares, J., Davies, B., Kushnir, S., Tonelli, C., Vittorioso, P., Kavanagh, T., Somssich, I., Coupland, G., Weisshaar, Bernd ; https://orcid.org/, Smeekens, S., Sablowski, R., Hordsworth, M., Ruberti, I., Droege-Laser, W., Engström, P., Zabeau, M., Valencia, A., Laux, T., Reindl, A., Parcy, F., Gilmartin, P., Giraudat, J., Costantino, P., Colombo, L., Gatz, C., Bäumlein, H., Mock, H.P., Traas, J., Ratcliff, F.   +99 more
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Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine

Metabolites, 2022
Metabolic fingerprinting by mass spectrometry aims at the comprehensive, semiquantitative analysis of metabolites. Isotope dilution, if successfully implemented, may provide a more reliable, relative quantification.
Fadi Fadil, Claudia Samol, Raffaela S. Berger, Fabian Kellermeier, Wolfram Gronwald, Peter J. Oefner, Katja Dettmer   +6 more
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Comparative Genomics and Functional Genomics Analysis in Plants

, 2023
Comparative genomics and functional genomics are two basic branches of plant genomics [...
Yaojia Chen, Jiacheng Wang, Quan Zou
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Genome-wide compendium and functional assessment of in vivo heart enhancers

Nature Communications, 2016
Identification of non-coding variants has outstripped our ability to annotate and interpret them. Dickel et al. present a compendium of over 80,000 putative human heart enhancers and demonstrate that two conserved enhancers are required for proper ...
Diane E. Dickel, Iros Barozzi, Yiwen Zhu, Yoko Fukuda-Yuzawa, Marco Osterwalder, Brandon J. Mannion, Dalit May, Cailyn H. Spurrell, Ingrid Plajzer-Frick, Catherine S. Pickle, Elizabeth Lee, Tyler H. Garvin, Momoe Kato, Jennifer A. Akiyama, Veena Afzal, Ah Young Lee, David U. Gorkin, Bing Ren, Edward M. Rubin, Axel Visel, Len A. Pennacchio   +20 more
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Development of a grid infrastructure for functional genomics [PDF]

, 2005
The BRIDGES project is incrementally developing and exploring database integration over six geographically distributed research sites with the framework of a Wellcome Trust biomedical research project (the Cardiovascular Functional Genomics project) to ...
Houghton, D., Bayer, M., Berry, D., Sinnott, R.O., Ferrier, M.   +4 more
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Functional Genomic Characterization of Cancer Genomes [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2016
International efforts to sequence cancer genomes now provide an overview of the major genetic alterations that occur in most human cancers. These studies have identified many highly recurrent alterations in specific cancer subtypes but have also identified mutations that occur at lower frequency and unstudied variants of known cancer-associated genes ...
Thomas P, Howard, Francisca, Vazquez, Aviad, Tsherniak, Andrew L, Hong, Mik, Rinne, Andrew J, Aguirre, Jesse S, Boehm, William C, Hahn   +7 more
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Harnessing Knowledge from Plant Functional Genomics and Multi-Omics for Genetic Improvement [PDF]

, 2023
Plant biology research has currently entered the post-genomics era with the advances in genomic technologies. The unprecedented development of genomics and application in crops is driving a new “green revolution” in agriculture.
G, Yang, Y, Li, J. Zeng, Y, Wang, Wan, Y., J., Zeng, Yin Li, Jian Zeng, Yaqiong Wang, Guangxiao Yang, Wan, Yongfang, Yongfang Wan   +11 more
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Endosperm transfer cell-specific genes and proteins: structure, function and applications in biotechnology

Frontiers in Plant Science, 2014
Endosperm transfer cells (ETC) are one of four main types of cells in endosperm. A characteristic feature of ETC is the presence of cell wall in-growths that create an enlarged plasma membrane surface area.
Sergiy eLopato, Nikolai eBorisjuk, Peter eLangridge, Maria eHrmova   +3 more
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