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浙江大学学报. 农业与生命科学版, 2008 The term virus-induced gene silencing' (VIGS) was first used to describe the phenomenon of recovery from virus infection, a natural plant antiviral mechanism, which recently has been exploited as a genetic technique involving recombinant viruses with a ...
XU You-ping +4 more
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Potato virus X-induced gene silencing in leaves and tubers of potato [PDF]
, 2004 Virus induced gene silencing (VIGS) is increasingly used to generate transient loss-of-function assays and has potential as a powerful reverse-genetics tool in functional genomic programs as a more rapid alternative to stable transformation. A previously
Loake, Gary J +17 more
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International Journal of Molecular Sciences, 2022 TRUE gene silencing is an RNA-mediated gene expression control technology and is termed after tRNase ZL-utilizing efficacious gene silencing. In this review, I overview the potentiality of small guide RNA (sgRNA) for TRUE gene silencing as novel therapeutics.
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Molecular Plant-Microbe Interactions, 2003 Promoters isolated from the Tomato leaf curl virus (TLCV) drive both constitutive and tissue-specific expression in transgenic tobacco. Following systemic TLCV infection of plants stably expressing TLCV promoter:GUS transgenes, transgene expression ...
Mark Seemanpillai +3 more
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Application of RNA Interference to Root-Knot Nematode Genes Encoding Esophageal Gland Proteins
Molecular Plant-Microbe Interactions, 2005 Plant parasitic nematodes have been, so far, refractory to transformation or mutagenesis. The functional analysis of nematode genes relies on the development of reverse genetic tools adapted to these obligate parasites.
M.-N. Rosso +4 more
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Cell Reports, 2022 Summary: X chromosome inactivation (XCI) is mediated by the non-coding RNA Xist, which directs chromatin modification and gene silencing in cis. The RNA binding protein SPEN and associated corepressors have a central role in Xist-mediated gene silencing.
Joseph S. Bowness +8 more
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The role of TNRC6 proteins in gene silencing [PDF]
, 2013 Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
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The post-transcriptional gene silencing pathway in Eucalyptus
Genetics and Molecular Biology, 2005 Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki +2 more
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The Whys and Wherefores of Transitivity in Plants
Frontiers in Plant Science, 2020 Transitivity in plants is a mechanism that produces secondary small interfering RNAs (siRNAs) from a transcript targeted by primary small RNAs (sRNAs). It expands the silencing signal to additional sequences of the transcript.
Felipe F. de Felippes +1 more
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Secondary siRNAs in Plants: Biosynthesis, Various Functions, and Applications in Virology
Frontiers in Plant Science, 2021 The major components of RNA silencing include both transitive and systemic small RNAs, which are technically called secondary sRNAs. Double-stranded RNAs trigger systemic silencing pathways to negatively regulate gene expression.
Neeti Sanan-Mishra +4 more
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