Results 21 to 30 of about 421,610 (258)

Genomic prediction in plants: opportunities for ensemble machine learning based approaches [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2023
Background: Many studies have demonstrated the utility of machine learning (ML) methods for genomic prediction (GP) of various plant traits, but a clear rationale for choosing ML over conventionally used, often simpler parametric methods, is still ...
Aalt D.J. van Dijk, Shahid Mansoor, Muhammad Farooq, Dick de Ridder, Harm Nijveen   +4 more
doaj   +1 more source

Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1

Cell Reports, 2022
Summary: X chromosome inactivation (XCI) is mediated by the non-coding RNA Xist, which directs chromatin modification and gene silencing in cis. The RNA binding protein SPEN and associated corepressors have a central role in Xist-mediated gene silencing.
Joseph S. Bowness, Tatyana B. Nesterova, Guifeng Wei, Lisa Rodermund, Mafalda Almeida, Heather Coker, Emma J. Carter, Artun Kadaster, Neil Brockdorff   +8 more
doaj   +1 more source

The post-transcriptional gene silencing pathway in Eucalyptus

Genetics and Molecular Biology, 2005
Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki, Tiago Campos-Pereira, Ivan de Godoy Maia   +2 more
doaj   +1 more source

The Whys and Wherefores of Transitivity in Plants

Frontiers in Plant Science, 2020
Transitivity in plants is a mechanism that produces secondary small interfering RNAs (siRNAs) from a transcript targeted by primary small RNAs (sRNAs). It expands the silencing signal to additional sequences of the transcript.
Felipe F. de Felippes, Peter M. Waterhouse   +1 more
doaj   +1 more source

Secondary siRNAs in Plants: Biosynthesis, Various Functions, and Applications in Virology

Frontiers in Plant Science, 2021
The major components of RNA silencing include both transitive and systemic small RNAs, which are technically called secondary sRNAs. Double-stranded RNAs trigger systemic silencing pathways to negatively regulate gene expression.
Neeti Sanan-Mishra, A. Abdul Kader Jailani, A. Abdul Kader Jailani, Bikash Mandal, Sunil K. Mukherjee   +4 more
doaj   +1 more source

MIGS as a Simple and Efficient Method for Gene Silencing in Rice

Frontiers in Plant Science, 2018
MiRNA-induced gene silencing (MIGS) technology is a special kind of RNA interference technology that uses miR173 to mediate the production of trans-acting siRNA (ta-siRNA) to achieve target gene silencing.
Xuelian Zheng, Lijia Yang, Qian Li, Linyi Ji, Aiting Tang, Lili Zang, Kejun Deng, Jianping Zhou, Yong Zhang   +8 more
doaj   +1 more source

Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction.

PLoS Genetics, 2022
Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing.
R A Greenstein, Henry Ng, Ramon R Barrales, Catherine Tan, Sigurd Braun, Bassem Al-Sady   +5 more
doaj   +1 more source

Visible gland constantly traces virus-induced gene silencing in cotton

Frontiers in Plant Science, 2022
A virus-induced gene silencing (VIGS) system was established to induce endogenous target gene silencing by post-transcriptional gene silencing (PTGS), which is a powerful tool for gene function analysis in plants.
Zhanfeng Si, Huaitong Wu, Huaitong Wu, Yue Tian, Zhiyuan Zhang, Tianzhen Zhang, Tianzhen Zhang, Yan Hu, Yan Hu   +8 more
doaj   +1 more source

Virus Recovery Is Induced in Brome mosaic virus p2 Transgenic Plants Showing Synchronous Complementation and RNA-2-Specific Silencing

Molecular Plant-Microbe Interactions, 2000
Nicotiana benthamiana plants expressing Brome mosaic virus (BMV) p2 protein complemented replication of RNAs1+3 but, surprisingly, supported little or no replication of RNA-2. Despite this, the p2 transgenic plants were able to support systemic migration
Lakshminarayan M. Iyer, Timothy C. Hall
doaj   +1 more source

A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5'-3' Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe. [PDF]

PLoS Genetics, 2016
Epigenetic gene silencing plays a critical role in regulating gene expression and contributes to organismal development and cell fate acquisition in eukaryotes.
James Franklin Tucker, Corina Ohle, Géza Schermann, Katja Bendrin, Wei Zhang, Tamás Fischer, Ke Zhang   +6 more
doaj   +1 more source