Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase [PDF]
PLoS Pathogens, 2018 Gene silencing is a natural antiviral defense mechanism in plants. For effective infection, plant viruses encode viral silencing suppressors to counter this plant antiviral response.
Linda Hanley-Bowdoin +2 more
exaly +3 more sources
Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq [PDF]
Nature Communications, 2017 There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with the nucleoplasmic protein Sfpq in an RNA-dependent fashion.
Silvia Bottini +11 more
doaj +6 more sources
MicroRNA chemical modifications in post-transcriptional gene silencing and human diseases [PDF]
Molecular Therapy: Nucleic AcidsMicroRNAs (miRNAs) are small, non-coding RNAs that influence various cellular activities through post-transcriptional gene silencing. Recent research has shown that miRNA modifications, including N6-methyladenosine (m6A), 5-methylcytidine (m5C), 2′-O ...
Amin Alaei, Pavan Kumar Kakumani
doaj +4 more sources
Exogenous miRNAs induce post-transcriptional gene silencing in plants. [PDF]
Nat Plants, 2021 AbstractPlants seem to take up exogenous RNA that was artificially designed to target specific genes, followed by activation of the RNA interference (RNAi) machinery. It is, however, not known whether plants use RNAs themselves as signalling molecules in plant-to-plant communication, other than evidence that an exchange of small RNAs occurs between ...
Betti F +11 more
europepmc +5 more sources
Beet Curly Top Iran Virus Rep and V2 Suppress Post-Transcriptional Gene Silencing via Distinct Modes of Action [PDF]
Viruses, 2023 Beet curly top Iran virus (BCTIV) is a yield-limiting geminivirus belonging to the becurtovirus genus. The genome organization of BCTIV is unique such that the complementary strand of BCTIV resembles Mastrevirus, whereas the virion strand organization is
Saeideh Ebrahimi +7 more
doaj +2 more sources
Post-Transcriptional Gene Silencing of Glucanase Inhibitor Protein in Phytophthora cinnamomi. [PDF]
Plants (Basel), 2023 Ink disease is considered one of the most significant causes contributing to the decline of chestnut orchards. The reduced yield of Castanea sativa Mill can be attributed to two main species: Phytophthora cinnamomi and Phytophthora cambivora, with the first being the main pathogen responsible for ink disease in Portugal. P.
Ferreira P +5 more
europepmc +5 more sources
Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus. [PDF]
World J Virol, 2015 While human immunodeficiency virus 1 (HIV-1) infection is controlled through continuous, life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is never completely eradicated from the body. Despite decades of research there is still no effective vaccine to prevent HIV-1 infection.
Méndez C, Ahlenstiel CL, Kelleher AD.
europepmc +4 more sources
The post-transcriptional gene silencing pathway in Eucalyptus [PDF]
Genetics and Molecular Biology, 2005 Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki +2 more
doaj +6 more sources
C4, the Pathogenic Determinant of Tomato Leaf Curl Guangdong Virus, May Suppress Post-transcriptional Gene Silencing by Interacting With BAM1 Protein [PDF]
Frontiers in Microbiology, 2020 Tomato leaf curl Guangdong virus (ToLCGdV) is a begomovirus associated with a Tomato yellow leaf curl disease (TYLCD) epidemic in Guangdong province, China.
Zhenggang Li +10 more
doaj +2 more sources
Post-transcriptional gene silencing in plants: a double-edged sword [PDF]
Science China Life Sciences, 2015 في النباتات، يحمي إسكات الجينات بعد النسخ (PTGS) الجينوم من الجينات الغريبة ويقيد التعبير عن بعض الجينات الداخلية من أجل النمو السليم. هنا، نستعرض التقدم الأخير حول كيفية تجنب PTGS غير المرغوب فيه في النباتات. كخطوة من خطوات صنع القرار في اختبار PTGS، يتم فرز النصوص الشاذة من معظم جينات الترميز الداخلية بدقة إلى مسارات اضمحلال الحمض النووي الريبي ثنائي
Hongwei Guo, Xinyan Zhang, Wu Huihui
exaly +3 more sources