Characteristics of post‐transcriptional gene silencing [PDF]
The EMBO Reports, 2001 A number of gene silencing phenomena that inactivate genes at the post-transcriptional level have been identified. Due to its potential for studying gene function, post-transcriptional gene silencing (PTGS) has become an intense area of research. In this review we describe the different means of inducing PTGS and discuss the possible biological roles ...
A. Chicas, MACINO, Giuseppe
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Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus. [PDF]
World J Virol, 2015 While human immunodeficiency virus 1 (HIV-1) infection is controlled through continuous, life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is never completely eradicated from the body. Despite decades of research there is still no effective vaccine to prevent HIV-1 infection.
Méndez C, Ahlenstiel CL, Kelleher AD.
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The post-transcriptional gene silencing pathway in Eucalyptus [PDF]
Genetics and Molecular Biology, 2005 Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki +2 more
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Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections
Biology, 2012 Gene silencing via non-coding RNA, such as siRNA and miRNA, can occur at the transcriptional, post-transcriptional, and translational stages of expression.
Fatah Kashanchi +7 more
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Post-Transcriptional Gene Silencing in Cultured Rice Cells [PDF]
Plant and Cell Physiology, 2000 Post-transcriptional gene silencing (PTGS) has been shown to occur in many transgenic dicotyledonous plants. Although transgene silencing has been documented in transgenic monocots, PTGS has been only recently described in monocotyledonous plants. To study PTGS in rice, we generated 25 transgenic rice cell lines in which the 35S-gus gene was stably ...
T, Kanno, S, Naito, K, Shimamoto
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Combinatorial action of miRNAs regulates transcriptional and post-transcriptional gene silencing following in vivo PNS injury. [PDF]
PLoS ONE, 2012 Injury response in the peripheral nervous system (PNS) is characterized by rapid alterations in the genetic program of Schwann cells. However, the epigenetic mechanisms modulating these changes remain elusive.
Tadepalli Adilakshmi +2 more
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Spreading of post‐transcriptional gene silencing along the target gene promotes systemic silencing
The Plant Journal, 2004 SummaryTransitive silencing and grafting‐induced gene silencing phenomena were combined to investigate whether a primary target β‐glucuronidase (gus) gene could promote the generation of systemic transitive silencing signals. Tobacco plants with hemizygous or homozygous silencer locus and in trans silenced primary target were used as a source of post ...
Rubén Darío, García-Pérez +2 more
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Gene Silencing: The Mechanism to Down Regulate the Target Gene [PDF]
International Journal of Bio-Resource and Stress Management, 2018 Gene silencing is one of the most efficient and promising functional genomics tools which down regulates the expression of a gene in a very precise manner and has significant impact on crop improvement.
Shreya +2 more
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Variables and Strategies in Development of Therapeutic Post-Transcriptional Gene Silencing Agents [PDF]
Journal of Ophthalmology, 2011 Post-transcriptional gene silencing (PTGS) agents such as ribozymes, RNAi and antisense have substantial potential for gene therapy of human retinal degenerations.
Jack M. Sullivan +5 more
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Exogenous miRNAs induce post-transcriptional gene silencing in plants. [PDF]
Nat Plants, 2021 AbstractPlants seem to take up exogenous RNA that was artificially designed to target specific genes, followed by activation of the RNA interference (RNAi) machinery. It is, however, not known whether plants use RNAs themselves as signalling molecules in plant-to-plant communication, other than evidence that an exchange of small RNAs occurs between ...
Betti F +11 more
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