Results 11 to 20 of about 255,778 (299)
The post-transcriptional gene silencing pathway in Eucalyptus [PDF]
Genetics and Molecular Biology, 2005 Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki +2 more
doaj +6 more sources
Exogenous miRNAs induce post-transcriptional gene silencing in plants. [PDF]
Nat Plants, 2021 AbstractPlants seem to take up exogenous RNA that was artificially designed to target specific genes, followed by activation of the RNA interference (RNAi) machinery. It is, however, not known whether plants use RNAs themselves as signalling molecules in plant-to-plant communication, other than evidence that an exchange of small RNAs occurs between ...
Betti F +11 more
europepmc +5 more sources
Post-Transcriptional Gene Silencing of Glucanase Inhibitor Protein in Phytophthora cinnamomi. [PDF]
Plants (Basel), 2023 Ink disease is considered one of the most significant causes contributing to the decline of chestnut orchards. The reduced yield of Castanea sativa Mill can be attributed to two main species: Phytophthora cinnamomi and Phytophthora cambivora, with the first being the main pathogen responsible for ink disease in Portugal. P.
Ferreira P +5 more
europepmc +5 more sources
Variables and Strategies in Development of Therapeutic Post-Transcriptional Gene Silencing Agents [PDF]
Journal of Ophthalmology, 2011 Post-transcriptional gene silencing (PTGS) agents such as ribozymes, RNAi and antisense have substantial potential for gene therapy of human retinal degenerations.
Jack M. Sullivan +5 more
doaj +3 more sources
Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus. [PDF]
World J Virol, 2015 While human immunodeficiency virus 1 (HIV-1) infection is controlled through continuous, life-long use of a combination of drugs targeting different steps of the virus cycle, HIV-1 is never completely eradicated from the body. Despite decades of research there is still no effective vaccine to prevent HIV-1 infection.
Méndez C, Ahlenstiel CL, Kelleher AD.
europepmc +4 more sources
Characteristics of post‐transcriptional gene silencing [PDF]
EMBO reports, 2001 A number of gene silencing phenomena that inactivate genes at the post‐transcriptional level have been identified. Due to its potential for studying gene function, post‐transcriptional gene silencing (PTGS) has become an intense area of research. In this review we describe the different means of inducing PTGS and discuss the possible biological roles ...
A. Chicas, MACINO, Giuseppe
openaire +3 more sources
Post-transcriptional gene silencing triggers dispensable DNA methylation in gene body in Arabidopsis. [PDF]
Nucleic Acids Res, 2019 Abstract Spontaneous post-transcriptional silencing of sense transgenes (S-PTGS) is established in each generation and is accompanied by DNA methylation, but the pathway of PTGS-dependent DNA methylation is unknown and so is its role.
Taochy C +7 more
europepmc +7 more sources
Virus‐Induced Gene Silencing, a Post Transcriptional Gene Silencing Method [PDF]
International Journal of Plant Genomics, 2009 Virus‐induced gene silencing (VIGS) is one of the reverse genetics tools for analysis of gene function that uses viral vectors carrying a target gene fragment to produce dsRNA which trigger RNA‐mediated gene silencing. There are a number of viruses which have been modified to silence the gene of interest effectively with a sequence‐specific manner ...
Unver, Turgay, Budak, Hikmet
openaire +3 more sources
Plants, 2022 Flavonoid biosynthesis requires the activities of several enzymes, which form weakly-bound, ordered protein complexes termed metabolons. To decipher flux regulation in the flavonoid biosynthetic pathway of chrysanthemum (Chrysanthemum morifolium Ramat ...
Sun-Hyung Lim +5 more
doaj +1 more source
eIF4GI facilitates the MicroRNA-mediated gene silencing. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional gene silencing by binding to complementary target mRNAs and recruiting the miRNA-containing ribonucleoprotein complexes to the mRNAs.
Incheol Ryu +4 more
doaj +1 more source