Results 31 to 40 of about 255,778 (299)

CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level [PDF]

open access: yes, 2018
Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific conditions.
Balsalobre, Carlos   +6 more
core   +4 more sources

Post-transcriptional gene silencing in a dynamic RNP world

open access: yesBiological Chemistry, 2023
Abstract MicroRNA (miRNA)-guided gene silencing is a key regulatory process in various organisms and linked to many human diseases. MiRNAs are processed from precursor molecules and associate with Argonaute proteins to repress the expression of complementary target mRNAs.
Simone Larivera   +2 more
openaire   +2 more sources

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context [PDF]

open access: yes, 2018
Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling ...
Abdel-Rahman, Mohamed H.   +736 more
core   +3 more sources

A Method to Produce vsiRNAs in Plants with Cross-Kingdom Gene Silencing Capacity

open access: yesApplied Sciences, 2022
Plants have evolved defense mechanisms to suppress viral transcription and replication by transcriptional and post-transcriptional gene silencing mediated by virus-derived small interfering RNAs (vsiRNAs).
Hernán de Jesús Villanueva-Alonzo   +11 more
doaj   +1 more source

RNA-Mediated Gene Silencing Signals Are Not Graft Transmissible from the Rootstock to the Scion in Greenhouse-Grown Apple Plants Malus sp. [PDF]

open access: yes, 2012
RNA silencing describes the sequence specific degradation of RNA targets. Silencing is a non-cell autonomous event that is graft transmissible in different plant species.
Bai   +37 more
core   +3 more sources

Transfer RNA-derived small RNAs in the cancer transcriptome [PDF]

open access: yes, 2016
The cellular lifetime includes stages such as differentiation, proliferation, division, senescence and apoptosis.These stages are driven by a strictly ordered process of transcription dynamics.
A Dueck   +38 more
core   +1 more source

A petunia ethylene-responsive element binding factor, PhERF2, plays an important role in antiviral RNA silencing. [PDF]

open access: yes, 2016
Virus-induced RNA silencing is involved in plant antiviral defense and requires key enzyme components, including RNA-dependent RNA polymerases (RDRs), Dicer-like RNase III enzymes (DCLs), and Argonaute proteins (AGOs).
Jiang, Cai-Zhong   +5 more
core   +1 more source

Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections

open access: yesBiology, 2012
Gene silencing via non-coding RNA, such as siRNA and miRNA, can occur at the transcriptional, post-transcriptional, and translational stages of expression.
Fatah Kashanchi   +7 more
doaj   +1 more source

Transcriptional and post-transcriptional regulation of RNAi-related gene expression during plant-virus interactions

open access: yesStress Biology, 2022
As sessile organisms, plants encounter diverse invasions from pathogens including viruses. To survive and thrive, plants have evolved multilayered defense mechanisms to combat virus infection.
Qian Gong   +4 more
doaj   +1 more source

RNA duplexes in transcriptional regulation

open access: yesBiomolecular Concepts, 2010
Transcriptional regulation by small RNA molecules, including small interfering RNA and microRNA, has emerged as an important gene expression modulator.
Swaminathan Sanjay   +3 more
doaj   +1 more source

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