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Identification of RNA silencing suppressor encoded by citrus chlorotic dwarf-associated virus [PDF]
Frontiers in MicrobiologyIntroductionCitrus chlorotic dwarf-associated virus (CCDaV) is an economically important citrus virus associated with leaf curling, deformation, and chlorosis found in China.
Xiao Ye +6 more
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Resistance gene Ty-1 restricts TYLCV infection in tomato by increasing RNA silencing [PDF]
Virology JournalA major antiviral mechanism in plants is mediated by RNA silencing through the action of DICER-like (DCL) proteins, which cleave dsRNA into discrete small RNA fragments, and ARGONAUTE (AGO) proteins, which use the small RNAs to target single-stranded RNA.
Xiaofang Ma +3 more
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Exploiting attP landing sites and gypsy retrovirus insulators to identify and study viral suppressors of RNA silencing [PDF]
Scientific ReportsRNA interference (RNAi) pathways are crucial for regulating viral infections in both animals and plants, acting as defense mechanisms that limit pathogen replication.
Adarsh K. Gupta +3 more
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Non-Coding RNA, 2021 RNA silencing pathways control eukaryotic gene expression transcriptionally or posttranscriptionally in a sequence-specific manner. In RNA silencing, the production of double-stranded RNA (dsRNA) gives rise to various classes of 20–24 nucleotide (nt ...
Xia Hua +5 more
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RNA decay is an antiviral defense in plants that is counteracted by viral RNA silencing suppressors. [PDF]
PLoS Pathogens, 2018 Exonuclease-mediated RNA decay in plants is known to be involved primarily in endogenous RNA degradation, and several RNA decay components have been suggested to attenuate RNA silencing possibly through competing for RNA substrates.
Fangfang Li, Aiming Wang
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Fungal Virus, FgHV1-Encoded p20 Suppresses RNA Silencing through Single-Strand Small RNA Binding
Journal of Fungi, 2022 Fungal viruses are widespread in fungi infecting plants, insects and animals. High-throughput sequencing has rapidly led to the discovery of fungal viruses. However, the interactive exploration between fungi and viruses is relatively limited.
Shuangchao Wang +5 more
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The VP3 factor from viruses of Birnaviridae family suppresses RNA silencing by binding both long and small RNA duplexes. [PDF]
PLoS ONE, 2012 RNA silencing is directly involved in antiviral defense in a wide variety of eukaryotic organisms, including plants, fungi, invertebrates, and presumably vertebrate animals.
Adrian Valli +6 more
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Cell Reports, 2015 The Piwi-interacting RNA (piRNA) pathway plays an essential role in the repression of transposons in the germline. Other functions of piRNAs such as post-transcriptional regulation of mRNAs are now emerging.
Bridlin Barckmann +11 more
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Mechanisms of resistance to viruses
Plant Protection Science, 2002 Resistance associated with a hypersensitive response (HR) and subsequent development of necrotic lesions (cell death) at the sites of virus infection can restrict virus movement in plants. Genes for HR are dominant and act on a gene-for-gene basis.
J.P.T. Valkonen
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RNA Silencing and Plant Viral Diseases
Molecular Plant-Microbe Interactions, 2012 RNA silencing plays a critical role in plant resistance against viruses, with multiple silencing factors participating in antiviral defense. Both RNA and DNA viruses are targeted by the small RNA-directed RNA degradation pathway, with DNA viruses being ...
Ming-Bo Wang +3 more
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