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Small RNAs play a critical role in the regulation of gene expression in diverse cellular processes. This mechanism, termed RNA silencing or RNAi, also functions as a defense mechanism against molecular parasites such as virus and transposon. Whereas RNA silencing is triggered by viral infection, viruses suppress RNA silencing to establish infection ...
MINE, Akira, OKUNO, Tetsuro
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Plant viruses encode virulence factors or RNA silencing suppressors to reprogram plant cellular processes or to fine-tune host RNA silencing-mediated defense responses.
Xiuling Yang +7 more
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Traffic into silence: endomembranes and post-transcriptional RNA silencing [PDF]
microRNAs (miRNAs) and small interfering RNAs (siRNAs) are small RNAs that repress gene expression at the post-transcriptional level in plants and animals. Small RNAs guide Argonaute-containing RNA-induced silencing complexes to target RNAs in a sequence-specific manner, resulting in mRNA deadenylation followed by exonucleolytic decay, mRNA ...
Kim, Yun Ju +2 more
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Root-Knot Nematode Parasitism Suppresses Host RNA Silencing
Root-knot nematodes damage crops around the world by developing complex feeding sites from normal root cells of their hosts. The ability to initiate and maintain this feeding site (composed of individual “giant cells”) is essential to their parasitism ...
E. Walsh, J. M. Elmore, C. G. Taylor
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Factors influencing Barley Stripe Mosaic Virus-mediated gene silencing in wheat [PDF]
Virus induced gene silencing (VIGS) is a technology that has been used primarily to target the virus genome in infected plants. However, if the virus genome carries inserts derived from the host plant, the system could be employed to target the mRNAs ...
Cakir, Cahid +3 more
core +1 more source
There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be self-regulated by feedback mechanisms. Diverse biological roles of these pathways have been established, including defence against viruses, regulation of gene ...
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RNA Silencing in Surgical Disease [PDF]
Each of our cells contains a complete copy of the genes required to create a whole organism. Thus, it was possible to clone Dolly from a single sheep epidermal cell, and we should be able to reconstruct a dinosaur from the genetic material buried in the mud of Jurassic Park.
Jyoti, Arya +3 more
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Suppression of RNA silencing by a plant DNA virus satellite requires a host calmodulin-like protein to repress RDR6 expression. [PDF]
In plants, RNA silencing plays a key role in antiviral defense. To counteract host defense, plant viruses encode viral suppressors of RNA silencing (VSRs) that target different effector molecules in the RNA silencing pathway.
Fangfang Li +3 more
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RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Jo Milner +4 more
core +1 more source
In plants, post-transcriptional gene silencing (PTGS) is a sequence-specific mechanism of RNA degradation induced by double-stranded RNA (dsRNA), which is processed into small interfering RNAs (siRNAs).
M. Carmen Cañizares +6 more
doaj +1 more source

