Results 11 to 20 of about 6,122,660 (302)
Small interfering RNAs in tendon homeostasis
British Medical Bulletin, 2021 Abstract Background Tenogenesis and tendon homeostasis are guided by genes encoding for the structural molecules of tendon fibres. Small interfering RNAs (siRNAs), acting on gene regulation, can therefore participate in the process of tendon healing ...
Francesco Oliva, Antonio Oliviero
exaly +3 more sources
Small interfering RNA; toward a new antiviral therapy [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2022 With the ability of viruses to mutate and introduce a high rate of diversity and continuous resistance to drug development, unique solutions are needed. RNA interference (RNAi) pathway as a natural defense mechanism mediated by plants, invertebrates, and
Engy Aziza
doaj +1 more source
Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
International Journal of Nanomedicine, 2012 Evelina Miele,1,* Gian Paolo Spinelli,2,* Ermanno Miele,3 Enzo Di Fabrizio,3,6 Elisabetta Ferretti,4 Silverio Tomao,2 Alberto Gulino,1,5 1Department of Molecular Medicine, 2Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University ...
Miele E +6 more
doaj +1 more source
Iron oxide nanoparticles and derivatives for biomedical imaging and application in cancer diagnosis and siRNA therapy [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Yigit, MV +2 more
core +6 more sources
Heliyon, 2023 Objective: Colorectal cancer remains a significant challenge with high mortality rates. The aim of this study was to investigate the effect of targeting the microRNA-148a/WNT10b axis with the long non-coding RNA LINC00261 on the proliferation and ...
Juanli Xi +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its eminence against several difficult-to-treat genetic disorders and other allied diseases.
Rushikesh Fopase +6 more
doaj +1 more source
Frontiers in Bioinformatics, 2022 The enzyme Dicer is a component of many small RNA (sRNA) pathways involved in RNA processing for post-transcriptional regulation, anti-viral response and control of transposable elements.
Ben Murcott +5 more
doaj +1 more source
Small Interfering RNA- Modern Approach for Intervening Pathological Conditions
NUST Journal of Natural Sciences, 2021 RNA interference (RNAi) refers to the inhibition of gene expression by small double-stranded RNA molecules. This technology can prove to be a breakthrough biological discovery of the decade as it has the potential to revolutionize the field of ...
Shazia Choudhary +7 more
doaj +1 more source
A small interfering RNA (siRNA) database for SARS-CoV-2
Scientific Reports, 2021 Coronavirus disease 2019 (COVID-19) rapidly transformed into a global pandemic, for which a demand for developing antivirals capable of targeting the SARS-CoV-2 RNA genome and blocking the activity of its genes has emerged.
Inácio Gomes Medeiros +5 more
doaj +1 more source
Small interfering RNA inhibition of Andes virus replication. [PDF]
PLoS ONE, 2014 Andes virus (ANDV) is the most common causative agent of hantavirus pulmonary syndrome (HPS) in the Americas, and is the only hantavirus associated with human-to-human transmission. Case fatality rates of ANDV-induced HPS are approximately 40%. There are
Cheng-Feng Chiang +3 more
doaj +1 more source