Results 161 to 170 of about 394,842 (259)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Identification and quantification of PFAS in the tap water of a French City, Besançon. [PDF]

Environ Monit Assess
Crini G, Mongioví C, Bradu C, Audonnet N, Yquel S, Lacalamita D.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Plasmonic and surface-enhanced Raman nanobiosensors for quantitative molecular detection. [PDF]

Discov Nano
Kim Y, Choi J, Lee S, Kim Y, Park J, Lee K, Cho E, Lee J, Lim KS, Kim HO.   +9 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Clinical implementation of a one-step no-wash flow cytometry method allows for real-time monitoring of patients treated with autologous CAR-T cells. [PDF]

Front Oncol
Salem N, Demerlé C, Mfarrej B, Blaison L, Lignée P, Couquiaud J, Ouffai S, Malenfant C, Reichert T, Demaret J, Trauet J, Yakoub-Agha I, Legrand Izadifar F, Granata A, Thévenet S, Château AL, Calmels B, Chabannon C, Brisou G, Lemarié C.   +19 more
europepmc   +1 more source

Limit of Blank (LOB), Limit of Detection (LOD), and Limit of Quantification (LOQ)

Organic & Medicinal Chemistry International Journal, 2018
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A robust dilute-and-inject ion chromatography - Tandem mass spectrometry for urinary glyphosate quantification. [PDF]

MethodsX
Louyer MV, Jabalot C, David A, Mercier F.   +3 more
europepmc   +1 more source

Robust Uncertainty Quantification for Measurement Problems with Limited Information [PDF]

, 2019
Basu, Tathagata, Einbeck, Jochen, Troffaes, Matthias C. M., Forbes, Alistair   +3 more
openaire   +1 more source