Results 171 to 180 of about 938,444 (341)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Comparison of Minimum Detectable Concentration with the IUPAC Detection Limit

open access: yesMeasurement Science Review, 2008
Janiga I., Mocak J., Garaj I.
doaj   +1 more source

Estimation of measurement error in plasma HIV-1 RNA assays near their limit of quantification. [PDF]

open access: yesPLoS One, 2017
Lima VD   +5 more
europepmc   +1 more source

When detection and quantification of mineral fibres in natural raw materials are at their limit – the case of a clay from the Gomsiqe–Puka mining area (Albania) [PDF]

open access: gold
Alessandro F. Gualtieri   +11 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Python code and data from Quantifying the limits of CAR T-cell delivery in mice and men

open access: green, 2021
Liam Brown   +4 more
openalex   +1 more source

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