CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Comparison of Minimum Detectable Concentration with the IUPAC Detection Limit
Janiga I., Mocak J., Garaj I.
doaj +1 more source
Estimation of measurement error in plasma HIV-1 RNA assays near their limit of quantification. [PDF]
Lima VD +5 more
europepmc +1 more source
When detection and quantification of mineral fibres in natural raw materials are at their limit – the case of a clay from the Gomsiqe–Puka mining area (Albania) [PDF]
Alessandro F. Gualtieri +11 more
openalex +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
seqBench: A Tunable Benchmark to Quantify Sequential Reasoning Limits of LLMs [PDF]
Mohammad Ramezanali +2 more
openalex +3 more sources
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A-003 Multisite Assessment of Commercial Quality Control Imprecision (testing from 2022 through to 2025) below the Limit of Quantification for a High-Sensitivity Cardiac Troponin I Assay [PDF]
Daniel Won Shik Choi +2 more
openalex +1 more source
(Un)measurability of violence - the limits of quantifying violence in contemporary societies [PDF]
Kristina Pejković
openalex +1 more source
Python code and data from Quantifying the limits of CAR T-cell delivery in mice and men
Liam Brown +4 more
openalex +1 more source

