Results 131 to 140 of about 39,459 (248)

Systemic sclerosis (Scleroderma) Among Adults Attending the Rheumatology Clinic of a Tertiary Institution

open access: yesAnnals of Health Research, 2016
Background: Systemic sclerosis is a multi-systemic autoimmune disorder characterised by the generation of autoantibodies, massive deposition of collagen and other matrix substances in the connective tissues and alterations of the microvasculature ...
Oguntona SA, Olatunde OA, Bakare BO
doaj  

Novel Combination of UVA‐1 Phototherapy With Topical Tofacitinib for Treating Eosinophilic Fasciitis With Morphea: Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Eosinophilic fasciitis (EF) and morphea are rare sclerosing connective tissue disorders, and there remains debate about whether these entities are pathologically distinct or related. This case report describes the successful treatment of an adolescent patient who developed progressive morphea plaques while being treated with systemic ...
Daphne M. Cheung   +5 more
wiley   +1 more source

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Edoardo Marrani   +5 more
wiley   +1 more source

New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review

open access: yesPharmaceuticals
Background: Juvenile scleroderma (JS) comprises a group of rare chronic autoimmune and fibrosing disorders in children, primarily presenting as juvenile localized scleroderma (jLS) or juvenile systemic sclerosis (jSS). While jLS predominantly affects the
Chiara Sassetti   +5 more
doaj   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

open access: yesPhotochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde   +6 more
wiley   +1 more source

Living in the Mycelial World

open access: yesTopics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source

Activity‐Based Functional Exercise for Disability in Systemic Sclerosis: Protocol for a Feasibility Randomised Controlled Trial

open access: yesMusculoskeletal Care, Volume 24, Issue 2, June 2026.
ABSTRACT Introduction Systemic Sclerosis (SSc) is associated with substantial disability in affected patients. Although exercise interventions for SSc have been developed, most focus on isolated body segments rather than global disability. Thus, this study aims to assess the feasibility of a functional activity‐based exercise programme designed to ...
Gabriela da Silva Santos   +7 more
wiley   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

open access: yesArthritis Care &Research, Volume 78, Issue 5, Page 582-590, May 2026.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai   +12 more
wiley   +1 more source

Dystrophic Calcinosis in a Patient with Scleroderma: Imaging Findings and Literature Review

open access: yesJournal of Mazandaran University of Medical Sciences, 2020
Subcutaneous calcinosis consists of abnormal calcium deposition in soft tissues and is one of the complications of scleroderma, especially in limited systemic sclerosis.
Maryam Mobini   +2 more
doaj  

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