Results 61 to 70 of about 39,459 (248)

Distinguishing between limited systemic scleroderma-associated pseudo-obstruction and peritoneal dissemination [PDF]

Surgical Case Reports, 2015
A 78-year-old woman receiving treatment for limited systemic scleroderma (SSc) underwent high anterior resection and partial liver resections for rectosigmoid colon cancer with multiple liver metastases. A year after surgery, an abdominal computed tomography (CT) demonstrated suspicion for peritoneal dissemination with an increase in ascites, and (18)F-
Saigusa, Susumu, Inoue, Yasuhiro, Ohi, Masaki, Imaoka, Hiroki, Uratani, Ryo, Kobayashi, Minako, Kusunoki, Masato   +6 more
openaire   +2 more sources

Biopsychosocial determinants of hand function and its trajectories over five years in patients with hand osteoarthritis

Arthritis Care &Research, Accepted Article.
Objectives This study aimed to investigate hand function trajectories over 5 years in primary hand osteoarthritis. Additionally, determinants of baseline and longitudinal hand function were assessed. Methods 538 patients with both baseline and 5‐year study visits were analyzed.
Annemiek V.E.M. Olde Meule, Coen van der Meulen, Jos Runhaar, Frits R. Rosendaal, Margreet Kloppenburg   +4 more
wiley   +1 more source

Comparison between clinical and immunological features of scleroderma with and without interstitial lung disease

Journal of the Pakistan Medical Association
The study was conducted at the Fauji Foundation Hospital, Rawalpindi, Pakistan, from January 1, 2023, to December 31, 2023, and comprised 20 female patients ages 18-55 years having scleroderma. Overall, 14(70%) patients had diffuse scleroderma and 6(30%)
Muhammad Salman Mushtaq, Haris Gul, Muhammad Umer Daraz, Muhammad khan, Saba Samreen   +4 more
doaj   +1 more source

Non-cirrhotic Portal Hypertension as the Initial Presentation of Limited Cutaneous Scleroderma: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2023
Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive skin fibrosis. It has 2 main clinical subtypes—diffuse cutaneous scleroderma and limited cutaneous scleroderma. Non-cirrhotic portal hypertension (NCPH) is defined as presence
Asif Ali Hitawala MD, Christopher Redmond MD, Edward W. Cowen MD, MHSc, David E. Kleiner MD, PhD, Sarfaraz Hasni MD, Theo Heller MD   +5 more
doaj   +1 more source

In systemic sclerosis skin perfusion of hands is reduced and may predict the occurrence of new digital ulcers [PDF]

, 2017
Systemic sclerosis (SSc) patients are at high risk for the development of ischemic digital ulcers (DUs). The aim of this study was to assess in SSc patients a correlation between skin perfusion evaluated by LDPI and DUs and to evaluate the prognostic ...
Barbano, Biagio, Barilaro, Giuseppe, Gasperini, Maria Ludovica, Gigante, Antonietta, Marra, Alessandro Maria, Quarta, Silvia, Rosato, Edoardo   +6 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]

, 2016
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M, Llado, A, Paolino, S, Pizzorni, C, Ruaro, B, Smith, Vanessa, Sulli, A   +6 more
core   +1 more source

Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Application of an iPSC‐Derived Organoid Model for Localized Scleroderma Therapy

Advanced Science, 2022
Localized scleroderma (LoS) is a rare chronic disease with extensive tissue fibrosis, inflammatory infiltration, microvascular alterations, and epidermal appendage lesions.
Jie Ma, Wei Li, Ruiyuan Cao, Dunqin Gao, Qiyu Zhang, Xiao Li, Biyou Li, Luye Lv, Mansheng Li, Junyi Jiang, Yujie Wang, Jun Li, Zhihong Wu, Yunping Zhu, Wu Zhong, Shuyang Zhang, Ling Leng   +16 more
doaj   +1 more source