Results 91 to 100 of about 1,272,092 (238)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Bringing the Social Back into Economies: Progress or Reductionism?. [PDF]
Section 2 of this paper suggests that economics has long sought to colonise other social sciences. It has, however, only achived limites success because of its alien methods and its need to take the social as given.
Fine, B.
core
Comprendre les représentations sociales pour comprendre les paysages. Potentiels et limites de la notion de services écosystémiques [PDF]
, 2017 Comprendre les représentations sociales pour comprendre les paysages.
Andrieu, Émilie +3 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
La visualización de datos y el arte de archivo: intersecciones, senderos y desvíos [PDF]
, 2018 Este artículo busca acercar varios conceptos desarrollados en las últimas décadas en el ámbito del arte basado en archivo para abordar el campo de producción simbólica de la visualización de datos.
Plazas, Hugo
core
, 2004 On s'intéresse à des problèmes mixtes pour des systèmes symétriques hyperboliques multidimensionnels semilinéaires perturbés par une petite viscosité. La description à la limite non visqueuse recquiert des développements du type BKW mettant en évidence ...
Sueur, Franck
core +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source