Results 81 to 90 of about 3,333,618 (304)
Condiciones y condicionamientos de la innovación social
Arbor: Ciencia, Pensamiento y Cultura, 2011 La innovación tiene condicionamientos y condiciones que limitan los espacios de actuación. Entre los más importantes están la relación con el cambio social, las limitaciones de la estructura social en las sociedades del conocimiento, los límites de la ...
Ander Gurrutxaga Abad
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
O fundamento ético da regulação econômica e seus limites no âmbito do estado constitucional
Opinión Jurídica, 2015 O presente trabalho tem por escopo investigar as bases epistemológicas que fundamentam a regulação estatal no âmbito da economia de livre mercado a partir das ideias do laissez-faire partilhadas pela escola de Viena.
Renato Braz Mehanna Khamis
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Anti-contos: de Diderot a Sena
Forma Breve, 2019 Análise do modo como dois textos (“Conto brevíssimo”, de Jorge de Sena, e “Isto não é um conto”, de Denis Diderot) exploram a subversão de diferentes princípios narrativos do conto, jogando não só com os seus elementos mais firmemente estabelecidos como
Diogo Fernandes
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Analyse critique des limites du libéralisme et du socialisme en Afrique [PDF]
Mouvements et Enjeux SociauxPartant de la nécessité de nouvelles approches du développement du continent résultant de « la crise même du développement », la présente étude explore les causes majeures du faible rendement de ces deux courants et leurs variantes en Afrique au niveau ...
MFUMUNTOTO BASANGA
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
European Journal for Philosophy of Science, 2018 Humeans take reality to be devoid of 'necessary connections': things just happen. Laws of nature are to be understood in terms of what 'just happens', not vice versa. Here the Humean needs some conception of what it is that 'just happens' - a conception of the Humean mosaic.
openaire +4 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source