Results 91 to 100 of about 3,333,618 (304)

Democracia no fio da navalha: limites e possibilidades para a implementação de uma agenda de Reforma Urbana no Brasil

open access: yes, 2009
Os anos 1990 representaram no Brasil avancos institucionais no campo do Direito a Moradia e a Cidade, com a incorporacao a Constituicao do pais, em 1988, dos principios da funcao social da cidade e da propriedade, do reconhecimento dos direitos de posse ...
Raquel Rolnik
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Privilegios. (Fragmentos de una consulta)

open access: yesEstudios de Derecho, 1919
Privilegios. (Fragmentos de una consulta)
Miguel Moreno Jaramillo
doaj  

Aplicabilidade dos limites da velocidade do ar para efeito de conforto térmico em climas quentes e úmidos

open access: yes, 2010
Este trabalho discute os limites dados para a velocidade do ar pelas normas ASHRAE 55 (2004) e ISO 7730 (2005). Para tal, realizou-se uma analise comparativa entre os valores-limite para a velocidade do ar definidos por essas normas e as respostas dos ...
Christhina Cândido   +3 more
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Mangroves Response to Climate Change: A Review of Recent Findings on Mangrove Extension and Distribution

open access: yesAnais da Academia Brasileira de Ciências, 2015
Mangroves function as a natural coastline protection for erosion and inundation, providing important environmental services. Due to their geographical distribution at the continent-ocean interface, the mangrove habitat may suffer heavy impacts from ...
Mario D.P. Godoy, Luiz D. de Lacerda
doaj   +1 more source

Indústrias criativas: definição, limites e possibilidades

open access: yes, 2009
O termo “industrias criativas” surgiu nos anos 1990, para designar setores nos quais a criatividade e uma dimensao essencial do negocio. As industrias criativas compreendem, entre outras, as atividades relacionadas ao cinema, ao teatro, a musica e as ...
P. Bendassolli   +3 more
semanticscholar   +1 more source

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