Results 221 to 230 of about 1,272,092 (238)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
[Characterisation of hypobaric hypoxia at 2240 metres above sea level]. [PDF]
Rev Med Inst Mex Seguro SocSantos-Martínez LE +5 more
europepmc +1 more source
[Breast cancer in Mauritania: a retrospective series of 200 cases at the National Oncology Center of Nouakchott]. [PDF]
Pan Afr Med JMamina AEH +4 more
europepmc +1 more source
Le Canada à la tête d’un mouvement international en faveur de services d’avortement accessibles et sécuritaires. [PDF]
Can Fam PhysicianPaynter M, Norman WV.
europepmc +1 more source