Results 41 to 50 of about 1,591,136 (269)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Disappearance

open access: yesOñati Socio-Legal Series, 2018
Life and death have been in the center of research on disappearance; disappearance is actually an unknown on those states: are they alive? Are they dead? Those unknowns are interwoven in a process where life and death constitute no longer a dichotomy and
Ignacio Irazuzta   +2 more
doaj   +1 more source

Fungal Pigments: Potential Coloring Compounds for Wide Ranging Applications in Textile Dyeing

open access: yesJournal of Fungi, 2020
Synthetic pigments/non-renewable coloring sources used normally in the textile industry release toxic substances into the environment, causing perilous ecological challenges.
Chidambaram Kulandaisamy Venil   +4 more
doaj   +1 more source

Closing the Adaptation Gap in Mountains

open access: yesMountain Research and Development, 2021
Over 1 billion people are living at the frontlines of climate change in mountain areas, where warming rates outpace the global average and are driving significant changes in environments and ecosystem services.
Graham McDowell   +10 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Adapting to climate change at the national level in Caribbean small island developing states

open access: yesIsland Studies Journal, 2018
Small island developing states (SIDS) are distinct from other developing countries: they are particularly and comparatively more vulnerable to the impacts of climate change.
Stacy-ann Robinson
doaj   +1 more source

Emergency remote education: A perspective of its potentialities and limitations in a Peruvian university

open access: yesTuning Journal for Higher Education, 2022
This research aims to identify the potentialities and limitations of emergency remote education in the Peruvian university context as a consequence of the COVID-19 pandemic based on teachers’ experience of the Hermilio Valdizán National University ...
Israel Barrutia Barreto   +1 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

La construction des appellations viticoles et la géographie juridique

open access: yesDéveloppement Durable et Territoires, 2015
Sometimes underestimated alliance, the geography and the law possess an intersection easy to conceive. Territories managed by societies call to the law and define limits asserting the passage of a mode of management in an other one.
Éric Rouvellac
doaj   +1 more source

Extension and Limits of Depolarization-Fringe Contrast Roughness Method in Sub-Micron Domain

open access: yesSensors, 2021
To guarantee quality standards for the industry, surface properties, particularly those of roughness, must be considered in many areas of application. Today, several methods are available on the market, but some damage the surface to be tested as they ...
Franziska Pöller   +4 more
doaj   +1 more source

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