Results 51 to 60 of about 64,070 (252)
Annales Universitatis Paedagogicae Cracoviensis. Studia Poetica, 2016 The limits of literary knowledge. On some new theories of interdisciplinarity (including one example) The paper consists of the review of a number of academic approaches to interdisciplinary research as represented by the Polish theorists of literature ...
Adrian Gleń
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Brouwer–Hilbert on the Limits of Mathematical Knowledge
Studia Universitatis Babeș-Bolyai. PhilosophiaBrouwer famously challenged the limits of mathematical knowledge by arguing that classical formalism obscures intuitive evidence. Hilbert, by contrast, considered that intuitive insights could safely be ignored as long as formal systems remained ...
Silviu-Constantin FEDEROVICI
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Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Odysseus "Božské komedie" a limity lidského vědění
Filosofický časopisThe goal of this text is to examine the morally devised limits of human knowledge using examples from an exposition of Odysseus’ journey beyond the Pillars of Heracles found in Canto XXVI of Dante’s Divine Comedy.
Jiráňová, Polina
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Mistisisme dalam Perspektif Filsafat Analitik: Antara Wittgenstein dan Mehdi Ha'iri Yazdi
Jurnal Filsafat, 2007 Language is a principal instrument for philosopher and as a medium for analysis and reflection. Wittgenstein said, that the order analytical philosophy is to clean away the epistemology from the "good" terms but unclear in it interpretation.
M. Hidayatullah S.
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Nature, 1994 Geophysical Inverse Theory. By Robert L. Parker R. L.. Princeton University Press: 1994. Pp. 386. £30r $39.50.
openaire +1 more source
The Limits of Causal Knowledge
, 2018 James M. Robins, Richard Scheines, Peter Spirtes, and Larry Wasserman.
James M. Robins (222887) +3 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source