Results 71 to 80 of about 64,070 (252)
Varieties of limits to scientific knowledge [PDF]
Complexity, 1998 Any area of knowledge is structured by an intricate interplay of limits, and joining. An apparently restrictive limit may actually reveal itself as liberating. We discuss the role that limits play in the real world, in our mathematical idealizations, and inthe mappings between them. We propose a classification of limits, and suggest how and when limits
Piet Hut, David Ruelle, Joseph F. Traub
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Limits to Internet Freedoms: Being Heard in an Increasingly Authoritarian World
, 2019 The Internet is a critical tool for communication and knowledge acquisition in societies across the globe. Unfortunately, its use has become a battlefield for governments, corporations, and individuals to censor speech and access to information.
Parks, Lisa +2 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Knowledge-how and the limits of defeat
Synthese, 2023 AbstractHow, if at all, is knowing how to do something defeasible? Some, the “intellectualists”, treat the defeasibility of knowledge-how as in some way derivative on the defeasibility of knowledge-that. According to a recent proposal by Carter and Navarro (Philos Phenomenol Res 3:662–685, 2017), knowledge-how defeat cannot be explained in terms of ...
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What Cost Knowledge Management? The Example of Infosys [PDF]
, 2013 The term knowledge management (KM) first came to prominence in the late 1990s. Although initially dismissed as a fad, KM continues to be featured in articles concerning business productivity and innovation.
Kimble, Chris
core +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Facts, skills and intuition : A typology of personal knowledge
, 2011 This paper introduces a knowledge model in which the types of knowledge are formed according to the nature of knowledge. First we use Ryle’s distinction of “that” and “how” knowledge, to which we add further three types. The five knowledge types are then
Baracskai, Zoltán +3 more
core
Communicating the Limits of our Knowledge
, 2020 We discuss whether social scientists do enough to communicate the limits of their knowledge in public ...
Gabriel Rossman +3 more
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source