Results 171 to 180 of about 167,013,277 (277)

Beyond prognosis: Identity, meaning, and existential uncertainty after severe brain injury. [PDF]

Palliat Support Care
Picon-Trevisanuto EWDS, Lacerda-Pereira F, Augusto-Rodrigues M, Macedo RM, de Camargo JD, Geber-Junior JC.   +5 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Effects of ecologically relevant acclimation temperature on upper thermal limits of juvenile Chinook salmon (<i>Oncorhynchus tshawytscha</i>). [PDF]

Conserv Physiol
Butler NA, Hinch SG, Lotto A, Lunzmann-Cooke EL, Birnie-Gauvin K, Eliason EJ.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

What Kafka's <i>Metamorphosis</i> reveals about consciousness without communication. [PDF]

Brain Commun
Demas A.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Windternet : Designing grid-liberated servers for regenerative energy communities

Imaginations of server practices that depend on renewable energy, such as wind or solar, highlight alternative paradigms to the fossil fuel intensive, resource hungry computation of cloud regimes.
Zapico, Jorge Luis, Snodgrass, Eric, Gustafsson, Daniel, Moss, Miranda, Pritchard, Helen V.   +4 more
core  

Rethinking Symptom Fluctuation in Multimorbidity: A Dynamic Systems Framework From Primary Care. [PDF]

J Eval Clin Pract
Matsuoka F.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Prognostication, neurologic injury, and the limits of registry data in trauma end-of-life care. [PDF]

Trauma Surg Acute Care Open
Bower KL.
europepmc   +1 more source