Results 41 to 50 of about 390 (142)
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
ESC Heart Failure, Volume 12, Issue 6, Page 4000-4020, December 2025.Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Lactylation in cancer: Advances and opportunities for treatment resistance
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.Aberrant lactylation plays a crucial role in the development of resistance to chemotherapy, immunotherapy, targeted therapy, and radiotherapy. Strategies to overcome this resistance include the inhibition of key glycolytic enzymes, targeting lactate transporters, synergistic therapeutic approaches, and the inhibition of specific site.
Keke Xu +10 more
wiley +1 more source
A Multifaceted Review on Neodiosmin In Planta Distribution, (Bio)synthesis, Food and Health Effects
Future Postharvest and Food, Volume 2, Issue 3, Page 237-247, September 2025.ABSTRACT Neodiosmin (NEO) is a major glycosylated flavone that is derived from the bitter flavanone neo‐hesperidin in citrus fruits including orange, lime, and lemon. One of the most important features of NEO is that it exerts a notable debittering effect on plant flavonoids justifying its wide use as a food additive.
Yuxuan Zhao +4 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 9, September 2025.Citri Sarcodactylis Fructus (CSF) has been shown to exhibit anti‐inflammatory, antioxidant, and anti‐obesity effects. However, its impact on the progression of acute lung injury (ALI) remains unclear. This study reveals that CSF alleviates LPS‐induced ALI by inhibiting NF‐κB signaling and NLRP3 inflammasome activation‐mediated inflammatory response ...
Zhuohui Luo +4 more
wiley +1 more source
The Impact of Limonin on Gut Microbiota
The FASEB Journal, 2016 The gut microbiota play critical roles in human health, and diet can modulate the compositions of the gut microbiota, which in turn may contribute to altered health outcomes such as changes in the risks of chronic diseases. Limonin is one of the major bioactive compounds found in citrus fruits and have been reported to possess various beneficial health
Min Gu +8 more
openaire +1 more source
Important flavonoids and limonin in selected Thai citrus residues
Journal of Functional Foods, 2013 The distributions of important flavonoids and limonin in selected Thai citrus residues were investigated in this study. The residues of interest were peels of pomelo (Citrus grandis (L.) Osbeck cv. Kao Yai and cv. Kao Nampheung), residues after juice extraction of tangerine (Citrus reticulata Blanco cv. Sainamphueng and cv.
Vaniya Chinapongtitiwat +3 more
openaire +2 more sources
Chukrasia tabularis limonoid plays anti-inflammatory role by regulating NF-κB signaling pathway in lipopolysaccharide-induced macrophages. [PDF]
Food Nutr Res, 2023 Shen J +7 more
europepmc +1 more source
, 1988 Limonin and ten structurally modified limonins were evaluated as antifeedants against 4th instar larvae of the Colorado potato beetle, Leptinotarsa decemlineata Say, in no-choice leaf dics assays.
Alford, A. R. +4 more
core
Studies in the chemistry of limonin
, 1960 Imperial Users ...
Sternhell, Sever, Sternhell, Sever
openaire +1 more source