Results 1 to 10 of about 2,725 (219)
Biological activities of gedunin—A limonoid from the meliaceae family [PDF]
Gedunin is an important limonoid present in several genera of the Meliaceae family, mainly in seeds. Several biological activities have been attributed to gedunin, including antibacterial, insecticidal, antimalarial, antiallergic, anti-inflammatory ...
Ana I. Oliveira +15 more
core +3 more sources
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Kethleen Duarte Crespo Soares +8 more
wiley +1 more source
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang +6 more
wiley +1 more source
Evaluation of limonoid production in suspension cell culture of Citrus sinensis
The use of cell and plant tissue culture techniques to produce economically important active metabolites has been growing. Among these substances are total limonoid aglycones, which are produced by “pera” orange (Citrus sinensis (L.) Osbeck, Rutaceae ...
Gonçalves, Regina Aparecida Correia +5 more
core +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Cedrela fissilis Vell. Inner Bark: LC–MS/MS‐Based Chemical Profiling and Toxicological Effects
ABSTRACT Investigating the mechanistic toxicity of plant extracts is essential for safety assessment. The predictive toxicological effects of Cedrela fissilis were evaluated, and LC–MS/MS‐based chemical profiling was performed. The hydroethanolic extract (HeECf) and ethyl acetate (EA) fraction were assessed in multimodel systems with different levels ...
Thainá Pereira da Silva Cabral +10 more
wiley +1 more source
ABSTRACT Pulmonary fibrosis (PF) is a complex and fatal interstitial lung disease in which the TGF‐β/Smad signaling pathway plays a pivotal role in fibrotic progression. However, strategies for precise modulation of this pathway remain limited. In this study, a bleomycin (BLM)‐induced mouse model of PF and TGF‐β‐stimulated MLE‐12 or primary lung ...
Yonghu Chen +5 more
wiley +1 more source
Cipadonoid A, a Novel Limonoid with an Unprecedented Skeleton, from Cipadessa cinerasecns
Cipadonoid A (1), a novel limonoid with an unprecedented skeleton, was isolated from the leaves of Cipadessa cinerasecns. Its structure and relative configuration were determined by spectroscopic analysis and computer modeling. 1 represents a new type of
Hai-Yang Liu (1391050) +8 more
core +1 more source
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Muhammet Mükerrem Kaya +4 more
wiley +1 more source

