Results 1 to 10 of about 357,237 (305)

Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1 [PDF]

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engraftment of gene-modified HSPCs in humanized mouse models.
Wannisa Khamaikawin   +13 more
doaj   +4 more sources

Potential Anti-HIV Agents from Marine Resources: An Overview

open access: yesMarine Drugs, 2010
Human immunodeficiency virus (HIV) infection causes acquired immune deficiency syndrome (AIDS) and is a global public health issue. Anti-HIV therapy involving chemical drugs has improved the life quality of HIV/AIDS patients.
Thanh-Sang Vo, Se-Kwon Kim
doaj   +3 more sources

Lectins with Anti-HIV Activity: A Review

open access: yesMolecules, 2015
Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics pradimicins and benanomicins, exhibit anti-HIV activity.
Ouafae Akkouh   +7 more
doaj   +3 more sources

Anti-HIV-1 HSPC-based gene therapy with safety kill switch to defend against and attack HIV-1 infection [PDF]

open access: yesMolecular Therapy: Methods & Clinical Development
Hematopoietic stem/progenitor cell (HSPC)-based anti-HIV-1 gene therapy holds promise to provide life-long remission following a single treatment. Here we report a multi-pronged anti-HIV-1 HSPC-based gene therapy designed to defend against and attack HIV-
Qi Guo   +7 more
doaj   +2 more sources

Exploring the role of topological descriptors to predict physicochemical properties of anti-HIV drugs by using supervised machine learning algorithms [PDF]

open access: yesBMC Chemistry
In order to explore the role of topological indices for predicting physio-chemical properties of anti-HIV drugs, this research uses python program-based algorithms to compute topological indices as well as machine learning algorithms.
Wakeel Ahmed   +5 more
doaj   +2 more sources

Investigation of genes coding for anti-HIV proteins MAP30 and MRK29 from Thai bitter melon (Momordica charantia L.) [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
Thai bitter melon, or Ma-Ra-Khee-Nok, is an M. charantia L. variety that is widely cultivated in Thailand. Thai bitter melon exhibits various pharmacological activities, including antidiabetic and antiviral. Many phytochemicals are found in various parts
Paktraporn Mekloy   +3 more
doaj   +1 more source

Synthesis of Isatin and its derivatives containing heterocyclic compounds

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2021
Isatin or 1H-indole-2,3-dione or 2,3-dioxindole is an indole derivative. Isatin and its analogs are synthetically useful substances where they may be utilized for the production of a broad range of heterocyclic molecules, which are depicting a wide reach
Pratibha MİSHRA   +4 more
doaj   +1 more source

Prediction of the anti-HIV activities of PETT analogs as non-nucleoside HIV-1 reverse transcriptase inhibitors by linear and non-linear QSAR models [PDF]

open access: yesشیمی کاربردی روز, 2015
Quantitative structure-activity relationship (QSAR) models were constructed in order to predict the anti-HIV activity of a set of phenethyl thiazole thiourea (PETT) analogs by calculated descriptors.
منصور عرب چم جنگلی   +3 more
doaj   +1 more source

Ganoderma: The mushroom of immortality [PDF]

open access: yesMicrobial Biosystems Journal, 2019
Ganoderma is the genus from order Aphyllophorales with more than 300 species. Ganoderma contains various compound that showed many biological activities e.g.
Shimaa El Mansy
doaj   +1 more source

HIV Seropositivity in Patients Admitted to Our Hospital: Six Year Evaluation

open access: yesDüzce Tıp Fakültesi Dergisi, 2021
Aim: Detecting human immunodeficiency virus (HIV)-infected individuals is very important in terms of quality of patients’ lives. However, it should be kept in mind that there may be false positives and tests must be confirmed. In this study, it was aimed
İlknur Esen Yıldız, İlkay Bahçeci
doaj   +1 more source

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