Results 41 to 50 of about 2,780,357 (303)

Anti-HIV drugs

Uirusu, 2013
Anti-HIV drugs are fall into the following 5 categories: nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), protease inhibitors (PIs), integrase strand transfer inhibitors (INSTIs), and C-C chemokine receptor type 5 (CCR5) inhibitors.
openaire   +3 more sources

Understanding the HIV care continuum [PDF]

Recent scientific advances have shown that antiretroviral therapy(ART) not only preserves the health of people living with HIV, but also dramatically lowers their risk of transmitting HIV to others by reducing the amount of virus in the body.

core   +6 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Anti-HIV drugs and the mitochondria

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2006
Several drugs are currently used that can significantly prolong the course of the infection with the human immunodeficiency virus (HIV), the cause of the acquired immunodeficiency syndrome (AIDS). Among these drugs, the nucleosidic inhibitors of viral reverse transcriptase can alter mitochondrial (mt) function by inhibiting the mitochondrial DNA ...
PINTI, Marcello, Salomoni P, COSSARIZZA, Andrea   +2 more
openaire   +3 more sources

Using age-specific mortality of HIV infected persons to predict anti-retroviral treatment need: a comparative analysis of data from five African population-based cohort studies. [PDF]

, 2012
OBJECTIVES: To present a simple method for estimating population-level anti-retroviral therapy (ART) need that does not rely on knowledge of past HIV incidence. METHODS: A new approach to estimating ART need is developed based on calculating age-specific
Kasamba, Ivan, Floyd, Sian, Milly Marston, Marston, Milly, Wringe, Alison, Till Bärnighausen, Alison Wringe, Gregson, Simon, Ivan Kasamba, Zaba, Basia, Basia Żaba, Bärnighausen, Till, Raphael Isingo, Kayuni, Ndoliwe, Constance Nyamukapa, Ndoliwe Kayuni, Herbst, Kobus, Nyamukapa, Constance, Todd, Jim, Kobus Herbst, Simon Gregson, Isingo, Raphael, Jim Todd, Sian Floyd   +23 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

HIV screening results of college group blood donors in Tianjin from 2012 to 2021

Zhongguo shuxue zazhi, 2022
Objective To analyze the infection characteristics and prevalence of HIV among college group voluntary blood donors in Tianjin, China, so as to provide data support for improving the promotion and recruitment strategies of voluntary blood donors ...
Caixia SHI, Jing FAN, Xue CHENG, Rui LIU
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

New Developments in Anti-HIV Chemotherapy [PDF]

Current Medicinal Chemistry, 2001
Abstract Virtually all the compounds that are currently used, or under advanced clinical trial, for the treatment of HIV infections, belong to one of the following classes: (i) nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs): i.e., zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir, emtricitabine ...
openaire   +6 more sources

Soroprevalência de marcadores da infecção pelo HBV e dos títulos de anti-HBs em indivíduos soropositivos para o HIV [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências de Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.As infecções pelo HIV e pelo HBV são preocupantes problemas de saúde pública, sendo que, a infecção ...
Martins, Saulo
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