Results 31 to 40 of about 5,751 (220)

Neem Derivatives Inhibits Tau Aggregation

open access: yesJournal of Alzheimer's Disease Reports, 2019
Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to
Nalini V. Gorantla   +4 more
doaj   +1 more source

Amelioration of Alzheimer’s Disease by Gut-Pancreas-Liver-Brain Interaction in an App Knock-In Mouse Model

open access: yesLife, 2021
In this study, we observed disease progression, changes in the gut microbiota, and interactions among the brain, liver, pancreas, and intestine in a mouse model of Alzheimer’s disease (AD), in addition to attempting to inhibit disease progression through
Mayumi Minamisawa   +7 more
doaj   +1 more source

Biological activities of limonoids in the Genus Khaya (Meliaceae): a review

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background Limonoids are a class of highly oxygenated modified triterpenoids with a diverse range of biological activities. Although with restricted occurrence in the plant kingdom, these compounds are found extensively in the Meliaceae and Rutaceae ...
Tomi Lois Olatunji   +2 more
doaj   +1 more source

Bitterness and antibacterial activities of constituents from Evodia rutaecarpa

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Bitter herbs are important in Traditional Chinese Medicine and the Electronic Tongue (e-Tongue) is an instrument that can be trained to evaluate bitterness of bitter herbs and their constituents.
Xiaoguang Liang   +6 more
doaj   +1 more source

Comparative study on secondary metabolites from different citrus varieties in the production area of Zhejiang

open access: yesFrontiers in Nutrition, 2023
To investigate the distribution pattern of bioactive components and their correlations between citrus varieties, we thoroughly analyzed secondary metabolites (including flavonoids, phenolic acids, carotenoids, and limonoids) in the peel and pulp of 11 ...
Mei Lin   +8 more
doaj   +1 more source

Limonoids and triterpenoids from the twigs and leaves of Dysoxylum hainanense [PDF]

open access: yes, 2012
Four new limonoids, dysohainanins A–D (1–4), and two new triterpenoids, dysohainanins E and F (5 and 6), together with seven known ones were isolated from the twigs and leaves of Dysoxylum hainanense Merr.
Gui-Hua Tang   +5 more
core   +1 more source

Impact of repeated NeemAzal®-treated blood meals on the fitness of Anopheles stephensi mosquitoes [PDF]

open access: yes, 2015
Background: Herbal remedies are widely used in many malaria endemic countries to treat patients, in particular in the absence of anti-malarial drugs and in some settings to prevent the disease.
ABAY, SOLOMON MEQUANENTE   +8 more
core   +5 more sources

Effects of Azadirachta indica seed kernel extracts on early erythrocytic schizogony of Plasmodium berghei and pro-inflammatory response in inbred mice [PDF]

open access: yes, 2019
Background: Medicinal plant research may contribute to develop new pharmacological control tools for vector borne diseases, such as malaria. Methods: The effects of methanol extracts (ME) obtained from seed kernel of ripe and unripe Azadirachta indica ...
Bruschi, F.   +11 more
core   +2 more sources

Germinating Seeds of a Good Source of Bioactive Limonoids

open access: yesNatural Product Communications, 2015
A simple method to obtain extracts enriched in bioactive limonoids from Citrus aurantium L. seeds has been developed, using solvents of increasing polarity.
Marta R. Ariza   +2 more
doaj   +1 more source

Carapanolides T–X from Carapa guianensis (Andiroba) Seeds

open access: yesMolecules, 2015
Two new mexicanolide-type limonoids, carapanolides T–U (1–2), and three new phragmalin-type limonoids, carapanolides V–X (3–5), were isolated from the seeds of Carapa guianensis (andiroba).
Teppei Miyake   +8 more
doaj   +1 more source

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