Results 31 to 40 of about 5,751 (220)
Neem Derivatives Inhibits Tau Aggregation
Tau is a phosphoprotein with natively unfolded conformation that functions to stabilize microtubules in axons. Alzheimer’s disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to
Nalini V. Gorantla +4 more
doaj +1 more source
In this study, we observed disease progression, changes in the gut microbiota, and interactions among the brain, liver, pancreas, and intestine in a mouse model of Alzheimer’s disease (AD), in addition to attempting to inhibit disease progression through
Mayumi Minamisawa +7 more
doaj +1 more source
Biological activities of limonoids in the Genus Khaya (Meliaceae): a review
Background Limonoids are a class of highly oxygenated modified triterpenoids with a diverse range of biological activities. Although with restricted occurrence in the plant kingdom, these compounds are found extensively in the Meliaceae and Rutaceae ...
Tomi Lois Olatunji +2 more
doaj +1 more source
Bitterness and antibacterial activities of constituents from Evodia rutaecarpa
Background Bitter herbs are important in Traditional Chinese Medicine and the Electronic Tongue (e-Tongue) is an instrument that can be trained to evaluate bitterness of bitter herbs and their constituents.
Xiaoguang Liang +6 more
doaj +1 more source
To investigate the distribution pattern of bioactive components and their correlations between citrus varieties, we thoroughly analyzed secondary metabolites (including flavonoids, phenolic acids, carotenoids, and limonoids) in the peel and pulp of 11 ...
Mei Lin +8 more
doaj +1 more source
Limonoids and triterpenoids from the twigs and leaves of Dysoxylum hainanense [PDF]
Four new limonoids, dysohainanins A–D (1–4), and two new triterpenoids, dysohainanins E and F (5 and 6), together with seven known ones were isolated from the twigs and leaves of Dysoxylum hainanense Merr.
Gui-Hua Tang +5 more
core +1 more source
Impact of repeated NeemAzal®-treated blood meals on the fitness of Anopheles stephensi mosquitoes [PDF]
Background: Herbal remedies are widely used in many malaria endemic countries to treat patients, in particular in the absence of anti-malarial drugs and in some settings to prevent the disease.
ABAY, SOLOMON MEQUANENTE +8 more
core +5 more sources
Effects of Azadirachta indica seed kernel extracts on early erythrocytic schizogony of Plasmodium berghei and pro-inflammatory response in inbred mice [PDF]
Background: Medicinal plant research may contribute to develop new pharmacological control tools for vector borne diseases, such as malaria. Methods: The effects of methanol extracts (ME) obtained from seed kernel of ripe and unripe Azadirachta indica ...
Bruschi, F. +11 more
core +2 more sources
Germinating Seeds of a Good Source of Bioactive Limonoids
A simple method to obtain extracts enriched in bioactive limonoids from Citrus aurantium L. seeds has been developed, using solvents of increasing polarity.
Marta R. Ariza +2 more
doaj +1 more source
Carapanolides T–X from Carapa guianensis (Andiroba) Seeds
Two new mexicanolide-type limonoids, carapanolides T–U (1–2), and three new phragmalin-type limonoids, carapanolides V–X (3–5), were isolated from the seeds of Carapa guianensis (andiroba).
Teppei Miyake +8 more
doaj +1 more source

