Results 51 to 60 of about 2,015 (176)

Obacunone Targets Serine–Threonine Kinase Receptor–Associated Protein to Promote the Formation of the TGF‐β/Smad7 Complex and Ameliorates Bleomycin‐Induced Pulmonary Fibrosis

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Pulmonary fibrosis (PF) is a complex and fatal interstitial lung disease in which the TGF‐β/Smad signaling pathway plays a pivotal role in fibrotic progression. However, strategies for precise modulation of this pathway remain limited. In this study, a bleomycin (BLM)‐induced mouse model of PF and TGF‐β‐stimulated MLE‐12 or primary lung ...
Yonghu Chen, Hongzhen Chen, Guangxi Li, Ning Li, Xuezheng Li, Zhe Jiang   +5 more
wiley   +1 more source

LIMONOIDS

, 1968
LIMONOIDS.
openaire   +1 more source

Extracts From Grapefruit (Citrus paradisi) Peel via Microwave‐Assisted and Conventional Extractions: Evaluation of Nosema Infection and Toxicity in Honey Bees

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Conventional and microwave‐assisted extractions of grapefruit peels were optimized using response surface methodology (RSM) based on TPC, TFC, and antioxidant activity (DPPH). The phytochemical profiles of the two optimum extracts were characterized via HPLC before evaluating their acute and chronic toxicity, as well as their effects on honey bee (Apis
Muhammet Mükerrem Kaya, Hidayet Tutun, Nilüfer Vural, Özlem Özmen, Samet Okuyan   +4 more
wiley   +1 more source

Phytotoxicity of Triterpenes and Limonoids from the Rutaceae and Meliaceae. 5α,6β,8α,12α-Tetrahydro-28-norisotoonafolin – a Potent Phytotoxin from

Natural Product Communications, 2015
Limonoids and triterpenes are the largest groups of secondary metabolites and have notable biological activities. Meliaceae and Rutaceae are known for their high diversity of metabolites, including limonoids, and are distinguished from other families due
Liliane Nebo, Rosa M. Varela, José M. G. Molinillo, Vanessa G. P. Severino, André L. F. Sarria, Cristiane M. Cazal, Maria Fátima das Graças Fernandes, João B. Fernandes, Francisco A. Macías   +8 more
doaj   +1 more source

Limonoids From

Natural Product Communications, 2020
Eight limonoids ( 1 - 8 ), including 1 new compound named as axillariol A ( 1 ), were isolated from the dichloromethane extract of Choerospondias axillaris branches and leaves using various chromatographic separations.
Nguyen Huu Toan Phan, Nguyen Thi Dieu Thuan, Nguyen Thi Thu Hien, Pham Van Huyen, Tran Thi Hong Hanh, Le Thi Vien, Tran Hong Quang, Nguyen Xuan Cuong, Nguyen Hoai Nam, Phan Van Kiem, Chau Van Minh   +10 more
doaj   +1 more source

Additives Promote Divergent Reactivity in Photolytic Deoxygenation and Lactonization Reactions of Cobalt Alkoxycarbonyls

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
We report a carbonylation‐homolysis process to access acyl radicals that can undergo decarboxylation or cyclization onto tethered alkenes. In both cases, ligands and additives are shown to influence the outcome to give saturated or unsaturated products, in some cases with isomerization of the initial products.
Jacob N. Hackbarth, Dana R. Chambers, Cory T. Ludwig, Tyler K. Brown, David B. C. Martin   +4 more
wiley   +1 more source

Bioactive Compounds of Citrus Fruits: A Review of Composition and Health Benefits of Carotenoids, Flavonoids, Limonoids, and Terpenes

Antioxidants, 2022
The increased consumption of fruits, vegetables, and whole grains contributes to the reduced risk of many diseases related to metabolic syndrome, including neurodegenerative diseases, cardiovascular disease (CVD), diabetes, and cancer.
Ramesh Kumar Saini, Arina Ranjit, Kavita Sharma, Parchuri Prasad, Xiaomin Shang, Karekal Girinur Mallikarjuna Gowda, Young-Soo Keum   +6 more
doaj   +1 more source

Combining Small‐Molecular Compounds With CAR T‐Cell Therapy: Novel Strategies for Enhanced Cancer Immunotherapy

Cancer Innovation, Volume 5, Issue 2, April 2026.
Chimeric antigen receptor (CAR) T‐cell therapy, although revolutionary for haematological malignancies, faces significant challenges, including T‐cell exhaustion, limited persistence, and treatment‐related toxicity. The integration of small‐molecule compounds offers a promising strategy to overcome these limitations.
Rangzi Yi, Zijian Zhang, Yang Yang, Haichuan Zhu   +3 more
wiley   +1 more source

Bactericidal, Bacteriostatic, and Fungicidal Activities of Clausena anisata Fruit and Its Compounds, Stigmasteryl 3‐Palmitate (a Phytosterol Ester) and Phellopterin (a Furanocoumarin), Against Some Clinical Pathogens

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
C. anisata fruit extract and its compounds demonstrated potent broad‐spectrum antimicrobial activity, notably against Klebsiella pneumoniae (MIC 0.625 mg/mL; MLC 2.5 mg/mL) and Candida albicans (MIC 0.0781 mg/mL; MLC 0.625 mg/mL). The findings highlight promising bactericidal and fungicidal potential of stigmasteryl 3‐palmitate and phellopterin against
Emmanuel Kofi Kumatia, Alex Asase, Prince Kyei Baffour, Borge Leth Frimpong, Ernest Agyei, Nguyen Huu Tung   +5 more
wiley   +1 more source

Chemical Compounds and Biologic Activities: A Review of Cedrela Genus

Molecules, 2020
The genus Cedrela P. Browne, which belongs to the Meliaceae family, has eighteen species. Trees of this genus are of economic interest due to wood quality, as well as being the focus of studies because of relevant biologic activities as in other ...
Thalya Soares R. Nogueira, Michel de S. Passos, Lara Pessanha S. Nascimento, Mayara Barreto de S. Arantes, Noemi O. Monteiro, Samyra Imad da S. Boeno, Almir de Carvalho Junior, Otoniel de A. Azevedo, Wagner da S. Terra, Milena Gonçalves C. Vieira, Raimundo Braz-Filho, Ivo J. Curcino Vieira   +11 more
doaj   +1 more source