Results 1 to 10 of about 11,220 (227)

Transcriptomics-Guided Investigation of the SLCG_Lrp Regulon Provides New Insights into Its Role for Lincomycin Biosynthesis [PDF]

Fermentation, 2023
Lincomycin industrially produced by Streptomyces lincolnensis can be adopted to treat infections caused by Gram-positive bacteria. SLCG_Lrp, a transcriptional regulator of the Lrp family, was first identified to positively regulate lincomycin ...
Yurong Xu, Wanlian Xu, Jing Yi, Binglin Li, Meng Liu, Maifei Zhang, Yang Zheng, Ruihua Liu, Hang Wu, Buchang Zhang   +9 more
doaj   +2 more sources

Complete genome sequence of high-yield strain S. lincolnensis B48 and identification of crucial mutations contributing to lincomycin overproduction

Synthetic and Systems Biotechnology, 2020
The lincosamide family antibiotic lincomycin is a widely used antibacterial pharmaceutical generated by Streptomyces lincolnensis, and the high-yield strain B48 produces 2.5 g/L lincomycin, approximately 30-fold as the wild-type strain NRRL 2936.
Ruida Wang, Fanjing Kong, Haizhen Wu, Bingbing Hou, Yajing Kang, Yuan Cao, Shiwei Duan, Jiang Ye, Huizhan Zhang   +8 more
doaj   +2 more sources

Verification of the efficacy of the gentamicin, tylosin, lincomycin, and spectinomycin antibiotic cocktail on frozen bovine semen [PDF]

Journal of Dairy Science
: Artificial insemination (AI) is a common method used internationally for breeding cattle but may have the potential to introduce pathogenic bacteria to naïve populations during the process.
Frank V. Pellegrini, Emily A. Caflisch, Nicole A. Aulik   +2 more
doaj   +2 more sources

Lincomycin [PDF]

, 2020
National Cancer Institute
openaire   +2 more sources

De Novo Design and Asymmetric Synthesis of a <i>C</i>-1/2 Benzodioxin Fused Glycoside Analogue of Lincomycin. [PDF]

Org Lett
Hicks I, Moradei R, Chiaraviglio L, Aljahdali AZ, Donthiri RR, Kirby JE, O'Doherty GA.   +6 more
europepmc   +3 more sources

High-capacity boronate affinity-based template-immobilized surface imprinted silica nanoparticles for rapid, selective, and efficient extraction and determination of lincomycin in milk and chicken

Frontiers in Sustainable Food Systems, 2023
BackgroundLincomycin, a natural antibiotic, is widely used by animal and fishery husbandries to prevent infections and treat diseases. It endangers people’s health when they eat foods containing lincomycin residue, especially the frequent consumption of ...
Yansong Zhang, Yihan Ding, Yidan Ma, Zixin Zhang, Yipei Wang, Daojin Li, Shuangshou Wang   +6 more
doaj   +1 more source

Simultaneous improvement of lincomycin A production and reduction of lincomycin B levels in Streptomyces lincolnensis using a combined medium optimization approach

Annals of Microbiology, 2022
Purpose The current study aimed to optimize the culture and production parameters of industrial production of lincomycin A by Streptomyces lincolnensis using a statistical approach that could also reduce unwanted by-products.
Xiu-hong Zheng, Rui-fang Ye, Qi-hang Ding, Feng-xian Hu, Hong-zhou Zhang, Shen Lai   +5 more
doaj   +1 more source

Evaluation of Zebrafish DNA Integrity after Individual and Combined Exposure to TiO₂ Nanoparticles and Lincomycin

Toxics, 2022
Environmental contamination by nanoparticles (NPs) and drugs represents one of the most debated issues of the last years. The aquatic biome and, indirectly, human health are strongly influenced by the negative effects induced by the widespread presence ...
Filomena Mottola, Concetta Iovine, Marianna Santonastaso, Vincenzo Carfora, Severina Pacifico, Lucia Rocco   +5 more
doaj   +1 more source

Transfer of enrofloxacin, ciprofloxacin, and lincomycin into eggshells and residue depletion in egg components after multiple oral administration to laying hens

Poultry Science, 2021
: Regardless of whether antimicrobial drugs are administered to laying hens legally or illegally, residues of these drugs may be present in the eggs. Even if the eggs are not intended for human consumption, byproducts/biowaste, such as eggshells, may ...
Małgorzata Gbylik-Sikorska, Beata Łebkowska-Wieruszewska, Anna Gajda, Ewelina Nowacka-Kozak, Andrzej Lisowski, Andrzej Posyniak   +5 more
doaj   +1 more source

Short-Term Lincomycin Exposure Depletion of Murine Microbiota Affects Short-Chain Fatty Acids and Intestinal Morphology and Immunity

Antibiotics, 2020
Lincomycin, as one of the most commonly used antibiotics, may cause intestinal injury, enteritis and other side effects, but it remains unknown whether these effects are associated with microbial changes and the effects of different doses of lincomycin ...
Shunfen Zhang, Ruqing Zhong, Hui Han, Bao Yi, Jie Yin, Liang Chen, Hongfu Zhang   +6 more
doaj   +1 more source