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Absorption of Lincomycin and Lincomycin Esters from Rat Jejunum [PDF]

open access: possibleJournal of Pharmaceutical Sciences, 1968
The absorption of lincomycin equivalents from rat intestinal loops was improved when short-chain (3 and 4 carbons) fatty acid esters of the drug were used. The 7-butyrate and 7-propionate esters of lincomycin appear to be absorbed more efficiently than corresponding 2-esters.
Heather M. Murray   +2 more
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The synthesis of lincomycin

Journal of the Chemical Society C: Organic, 1970
Methyl 6-amino-6,8-dideoxy-1-thio-D-erythro-α-D-galacto-octopyranoside(16), the intact carbohydrate portion of the antibiotic lincomycin (1), has been synthesised from D-galactose. The amino-alcohol side chain was attached to 1,2:3,4-di-O-isopropylidene-α-D-galacto-hexodialdopyranose-(1,5)(2) by two independent procedures, and the glycosidic thiomethyl
Walter A. Szarek   +2 more
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The mode of action of lincomycin

Biochemical and Biophysical Research Communications, 1964
Abstract The discovery, isolation and antibacterial properties of the antibiotic lincomycin have been reported recently ( Mason et al , 1962 ; Herr et al , 1962 ; Lewis et al , 1962 ). This paper is concerned with the mode of action of lincomycin.
Paris M. Allen, John J. Josten
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