Results 211 to 220 of about 19,031 (249)
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Actinomycosis Treated With Lincomycin
JAMA: The Journal of the American Medical Association, 1970Actinomycosis in four patients allergic to penicillin has been treated successfully with lincomycin hydrochloride monohydrate. The rapid good response suggests that lincomycin offers a satisfactory substitute for penicillin in allergic individuals.
Everett R. Rhoades +2 more
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Lincomycin, clindamycin and their applications
Applied Microbiology and Biotechnology, 2004Lincomycin and clindamycin are lincosamide antibiotics used in clinical practice. Both antibiotics are bacteriostatic and inhibit protein synthesis in sensitive bacteria. They may even be bactericidal at the higher concentrations that can be reached in vivo. Clindamycin is usually more active than lincomycin in the treatment of bacterial infections, in
T Rezanka, J Spízek
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1972
Publisher Summary This chapter reviews lincomycin, which is a basic compound consisting of the propylhygric acid amide of a methyl thiooctopyranoside. Cylinder plate method involves maintaining Sarcina lutea ATCC 9341 on slants of G & R No. 1 agar and transfer weekly to fresh slants. The tube is to be incubated for 24 h. The next step involves washing
D.J. Mason, Walter T. Sokolski
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Publisher Summary This chapter reviews lincomycin, which is a basic compound consisting of the propylhygric acid amide of a methyl thiooctopyranoside. Cylinder plate method involves maintaining Sarcina lutea ATCC 9341 on slants of G & R No. 1 agar and transfer weekly to fresh slants. The tube is to be incubated for 24 h. The next step involves washing
D.J. Mason, Walter T. Sokolski
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The safety of lincomycin in pregnancy
American Journal of Obstetrics and Gynecology, 1975The progeny of mothers treated with lincomycin during the first, second, or third trimester of their pregnancy were extensively evaluated at various periods extending to 7 years after birth. As compared to a control group (mothers not receiving lincomycin), the study group did not show any more developmental anomalies of the teeth, specific physical ...
J.D. Panzer, Abe Mickal
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1971
Publisher Summary The chapter gives an account of the modification of lincomycin. The fermentation broth of streptomyces lincolnensis var. lincolnensis, a new species of streptomycete isolated from a soil sample collected in Gering, Nebraska, was found to contain a new antibiotic, named lincomycin.
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Publisher Summary The chapter gives an account of the modification of lincomycin. The fermentation broth of streptomyces lincolnensis var. lincolnensis, a new species of streptomycete isolated from a soil sample collected in Gering, Nebraska, was found to contain a new antibiotic, named lincomycin.
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Journal of Pharmaceutical Sciences, 1965
Lincomycin degrades slowly in 0.1 N HCl at 70° (half-life, 39 hr.), and the decrease in optical rotation shows a direct correlation with microbiological assays. At 37°, lincomycin shows no degradation for at least 48 hr. in 0.1 N HCl. Under these conditions, penicillin V degrades with a half-life of 29 min.
Max E. Royer +2 more
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Lincomycin degrades slowly in 0.1 N HCl at 70° (half-life, 39 hr.), and the decrease in optical rotation shows a direct correlation with microbiological assays. At 37°, lincomycin shows no degradation for at least 48 hr. in 0.1 N HCl. Under these conditions, penicillin V degrades with a half-life of 29 min.
Max E. Royer +2 more
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Oral Surgery, Oral Medicine, Oral Pathology, 1970
Abstract Lincomycin has proved to be an effective drug in treating staphylococcus infections. It is easy to administer orally and is well tolerated in doses of 500 mg. four times a day for prolonged periods of time. Its effectiveness against bone infections is attributed to its ability to penetrate bone and severely infected tissue.
Ved M. Khosla, Ved M. Khosla
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Abstract Lincomycin has proved to be an effective drug in treating staphylococcus infections. It is easy to administer orally and is well tolerated in doses of 500 mg. four times a day for prolonged periods of time. Its effectiveness against bone infections is attributed to its ability to penetrate bone and severely infected tissue.
Ved M. Khosla, Ved M. Khosla
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1978
Lincomycin derives its name from Lincoln, Nebraska. The antibiotic was isolated from a soil organism Streptomyces lincolnensis found in this area and it was first introduced in 1963. Lincomycin differs chemically from most other available antibiotics.
J. A. Gray, J. McM. Murdoch, A. P. Ball
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Lincomycin derives its name from Lincoln, Nebraska. The antibiotic was isolated from a soil organism Streptomyces lincolnensis found in this area and it was first introduced in 1963. Lincomycin differs chemically from most other available antibiotics.
J. A. Gray, J. McM. Murdoch, A. P. Ball
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Mass spectra of lincomycin, lincomycin analogs and degradation products
Organic Mass Spectrometry, 1972AbstractThe principal ions observed in the mass spectra of lincomycin hydrochloride, some of its analogs and two degradation products are discussed. Lincomycin‐related compounds can be characterized by examination of the molecular ion and four other ions. Plausible mechanistic interpretations of these ions are presented.
Marvin F. Grostic, Fred Kagan
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LINCOMYCIN AS A CAUSE OF PSEUDOMEMBRANOUS COLITIS
The Lancet, 1973Abstract Eight patients with pseudomembranous colitis are described. In seven of the eight the administration of lincomycin preceded the illness. Three of these patients died. An association between pseudomembranous colitis and lincomycin is supported by the frequency with which the disease has been diagnosed since the widespread introduction of the ...
AlisterJ. Scott +2 more
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