Results 21 to 30 of about 95,332 (230)

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1986
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1245/thumbnail ...

core   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin   +14 more
wiley   +1 more source

Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]

open access: yes, 1987
To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Bale, J. F.   +4 more
core   +1 more source

Quasi‐Bound States in the Continuum on the Bloch‐Surface‐Wave Platform for Sensing With Simultaneous High Q‐Factor and High Sensitivity

open access: yesAdvanced Optical Materials, EarlyView.
Quasi‐bound states in the continuum on the Bloch surface wave platform are demonstrated, exhibiting high Q‐factors due to strongly suppressed radiative losses and high sensitivity arising from the large evanescent field inherent to the surface wave. The resonance shows clear shifts after each surface molecular functionalization step, highlighting its ...
Bo‐Wei Lin   +6 more
wiley   +1 more source

No evidence of spread of Linda pestivirus in the wild boar population in Southern Germany

open access: yesVirology Journal
Lateral-shaking inducing neuro-degenerative agent virus (LindaV) is a novel member of the highly diverse genus Pestivirus within the family Flaviviridae.
Doreen Schulz   +3 more
doaj   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

Modulation of ADAM17 Levels by Pestiviruses Is Species-Specific

open access: yesViruses
Upon host cell infection, viruses modulate their host cells to better suit their needs, including the downregulation of virus entry receptors. ADAM17, a cell surface sheddase, is an essential factor for infection of bovine cells with several pestiviruses.
Hann-Wei Chen   +6 more
doaj   +1 more source

A Petunia homeodomain-leucine zipper protein, PhHD-Zip, plays an important role in flower senescence. [PDF]

open access: yes, 2014
Flower senescence is initiated by developmental and environmental signals, and regulated by gene transcription. A homeodomain-leucine zipper transcription factor, PhHD-Zip, is up-regulated during petunia flower senescence. Virus-induced gene silencing of
Chang, Xiaoxiao   +5 more
core   +3 more sources

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

open access: yesAdvanced Science, EarlyView.
Fibroblast activation protein alpha‐positive (FAPα+) macrophages, a distinct subset of multiple myeloma (MM)‐associated macrophages, drive immune evasion in MM through multi‐faceted mechanisms. FAPα physically interacts with vimentin (VIM) and triggers its phosphorylation at the S72 residue, which in turn induces PD‐L1 transcription. Additionally, FAPα
Huiyao Gu   +15 more
wiley   +1 more source

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