Isolation and Molecular Characterization of Atypical Porcine Pestivirus Emerging in China [PDF]
Viruses, 2023 Atypical porcine pestivirus (APPV) is a recently discovered and very divergent species of the genus Pestivirus within the family Flaviviridae, which causes congenital tremor (CT) in newborn piglets.
Hua-Ji Qiu, Yuzi Luo, Qiu Hua-Ji
exaly +6 more sources
Detection and investigation of atypical porcine pestivirus in a swine production system [PDF]
Frontiers in Veterinary Science, 2022 A commercial farrow-to-finish farm was suspicious of atypical porcine pestivirus (APPV) after observing clinical signs of congenital tremors (CT) and splay leg (SL) of newborn pigs.
Cassandra Jones +2 more
exaly +6 more sources
Disruption of interferon-β production by the Npro of atypical porcine pestivirus [PDF]
Virulence, 2021 Atypical porcine pestivirus (APPV) is an emerging porcine virus that threatens global swine production. Pestiviruses can prevent interferon (IFN) production to avoid the host innate immune response, and the Npro viral protein can play a critical role ...
Huiguang Wu +2 more
exaly +6 more sources
Phylogenetic and codon usage analysis of atypical porcine pestivirus (APPV) [PDF]
Virulence, 2020 Atypical porcine pestivirus (APPV) has been identified as the main causative agent for congenital tremor (CT) type A-II in piglets, which is threatening the health of the global swine herd. However, the evolution of APPV remains largely unknown.
Huiguang Wu +2 more
exaly +6 more sources
Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds [PDF]
Viruses, 2021 Atypical porcine pestivirus (APPV) was first discovered in North America in 2015 and was later shown to be associated with congenital tremor (CT) in piglets. CT is an occasional challenge in some Danish sow herds. Therefore, we initiated an observational
Anette Bøtner, Thomas Bruun Rasmussen
exaly +9 more sources
Development of a Crystal Digital RT-PCR for the Detection of Atypical Porcine Pestivirus [PDF]
Veterinary Sciences, 2023 Atypical porcine pestivirus (APPV), a newly discovered virus, is associated with the type A-II congenital tremor (CT) in neonatal piglets. APPV distributes throughout the world and causes certain economic losses to the swine industry.
Hongbin Si, Kaichuang Shi, Huixin Liu
exaly +6 more sources
Long-Term Circulation of Atypical Porcine Pestivirus (APPV) within Switzerland [PDF]
Viruses, 2019 In 2015, a new pestivirus was described in pig sera in the United States. This new “atypical porcine pestivirus” (APPV) was later associated with congenital tremor (CT) in newborn piglets.
Alexander Grahofer +2 more
exaly +10 more sources
Atypical Porcine Pestivirus Circulation and Molecular Evolution within an Affected Swine Herd [PDF]
Viruses, 2020 Atypical porcine pestivirus (APPV) is a single-stranded RNA virus from the family Flaviviridae, which is linked to congenital tremor (CT) type A-II in newborn piglets.
Ad De Groof +2 more
exaly +7 more sources
DNAJC14-Independent Replication of the Atypical Porcine Pestivirus [PDF]
Journal of Virology, 2022 DNAJC14 is an essential cofactor of the pestiviral NS2 autoprotease, limiting replication to tolerable levels as a prerequisite for the noncytopathogenic biotype of pestiviruses. Surprisingly, we found that the atypical porcine pestivirus (APPV) is able to replicate in the absence of DNAJC14.
Norbert Tautz +2 more
exaly +4 more sources
The Diversity and Spatiotemporally Evolutionary Dynamic of Atypical Porcine Pestivirus in China [PDF]
Frontiers in Microbiology, 2022 The presence of congenital tremor (CT) type A-II in newborn piglets, caused by atypical porcine pestivirus (APPV), has been a focus since 2016. However, the source, evolutionary history, and transmission pattern of APPV in China remain poorly understood.
Hailong Ma +14 more
doaj +4 more sources