Results 1 to 10 of about 501 (101)
Isolation and Molecular Characterization of Atypical Porcine Pestivirus Emerging in China [PDF]
Viruses, 2023 Atypical porcine pestivirus (APPV) is a recently discovered and very divergent species of the genus Pestivirus within the family Flaviviridae, which causes congenital tremor (CT) in newborn piglets. In this study, an APPV epidemiological investigation was conducted by studying 975 swine samples (562 tissue and 413 serum samples) collected from ...
Hao Song, Hua-Ji Qiu, Yuzi Luo
exaly +5 more sources
DNAJC14-Independent Replication of the Atypical Porcine Pestivirus [PDF]
Journal of Virology, 2022 DNAJC14 is an essential cofactor of the pestiviral NS2 autoprotease, limiting replication to tolerable levels as a prerequisite for the noncytopathogenic biotype of pestiviruses. Surprisingly, we found that the atypical porcine pestivirus (APPV) is able to replicate in the absence of DNAJC14.
Norbert Tautz, Benjamin Lamp
exaly +4 more sources
Phylogenetic and codon usage analysis of atypical porcine pestivirus (APPV) [PDF]
Virulence, 2020 Atypical porcine pestivirus (APPV) has been identified as the main causative agent for congenital tremor (CT) type A-II in piglets, which is threatening the health of the global swine herd. However, the evolution of APPV remains largely unknown. In this study, phylogenetic analysis showed that APPV could be divided into three phylogroups (I, II, and ...
Chunxiao Mou +2 more
exaly +6 more sources
Detection of Atypical Porcine Pestivirus in Piglets from Danish Sow Herds [PDF]
Viruses, 2021 Atypical porcine pestivirus (APPV) was first discovered in North America in 2015 and was later shown to be associated with congenital tremor (CT) in piglets. CT is an occasional challenge in some Danish sow herds. Therefore, we initiated an observational case control study to clarify a possible relationship between CT and APPV in Danish pig production.
Charlotte Sonne Kristensen +2 more
exaly +8 more sources
Genetic diversity and detection of atypical porcine pestivirus infections. [PDF]
J Anim Sci, 2022 Abstract Atypical porcine pestivirus (APPV), an RNA virus member of the Flaviviridae family, has been associated with congenital tremor in newborn piglets. Previously reported quantitative polymerase chain reaction (qPCR)–based assays were unable to detect APPV in novel cases of congenital tremor originated from multiple farms from U.S ...
Sutton KM +6 more
europepmc +3 more sources
Detection and investigation of atypical porcine pestivirus in a swine production system. [PDF]
Front Vet Sci, 2022 A commercial farrow-to-finish farm was suspicious of atypical porcine pestivirus (APPV) after observing clinical signs of congenital tremors (CT) and splay leg (SL) of newborn pigs. If introduced onto the farrow-to-finish, the two potential routes of introduction could be through replacement gilts or incoming semen doses. Therefore, this study aimed to
Houston GE +6 more
europepmc +4 more sources
Atypical porcine pestivirus—A widespread virus in the Swedish wild boar population [PDF]
Transboundary and Emerging Diseases, 2021 AbstractThe recently identified causative agent of congenital tremor in domestic piglets, atypical porcine pestivirus (APPV), was detected in serum from Swedish wild boar. A previous study from Sweden described APPV in domestic piglets suffering from congenital tremor, but the APPV situation in the wild boar population was unknown.
Hedvig Stenberg +5 more
openaire +4 more sources
The Diversity and Spatiotemporally Evolutionary Dynamic of Atypical Porcine Pestivirus in China. [PDF]
Front Microbiol, 2022 The presence of congenital tremor (CT) type A-II in newborn piglets, caused by atypical porcine pestivirus (APPV), has been a focus since 2016. However, the source, evolutionary history, and transmission pattern of APPV in China remain poorly understood.
Ma H +6 more
europepmc +4 more sources
Development of a Crystal Digital RT-PCR for the Detection of Atypical Porcine Pestivirus. [PDF]
Vet Sci, 2023 Atypical porcine pestivirus (APPV), a newly discovered virus, is associated with the type A-II congenital tremor (CT) in neonatal piglets. APPV distributes throughout the world and causes certain economic losses to the swine industry. The specific primers and probe were designed targeting the 5′ untranslated region (UTR) of APPV to amplify a 90 bp ...
Liu H +5 more
europepmc +4 more sources
Disruption of interferon-β production by the Npro of atypical porcine pestivirus. [PDF]
Virulence, 2021 Atypical porcine pestivirus (APPV) is an emerging porcine virus that threatens global swine production. Pestiviruses can prevent interferon (IFN) production to avoid the host innate immune response, and the Npro viral protein can play a critical role. Knowledge of the host immune response to APPV infection is limited.
Mou C, Pan S, Wu H, Chen Z.
europepmc +5 more sources