Distribution and persistence of atypical porcine pestivirus in experimentally inoculated pigs. [PDF]
Atypical porcine pestivirus (APPV) is a cause of congenital tremors (CTs) in piglets and has been found in swine populations around the globe. Although systemic distribution of the virus has been reported, there is limited information regarding viral localization at the cellular level and distribution at the tissue level.
Buckley AC +8 more
europepmc +3 more sources
Genetic characterization and recombination analysis of atypical porcine pestivirus
Atypical porcine pestivirus (APPV) is recognised as the etiology of congenital tremor (CT) Type A-II and poses a challenge to pig production. Here, we described a CT case in piglets caused by APPV infection in central China in 2017. Interestingly, different from a previous report, more CT litters were observed in the second and third parity sows ...
Leyi Wang +2 more
exaly +3 more sources
Atypical Porcine Pestivirus (APPV) as a New Species of Pestivirus in Pig Production. [PDF]
The genus Pestivirus, which belongs to the family Flaviviridae, includes ssRNA+ viruses responsible for infectious diseases in swine, cattle, sheep, goats, and other domestic and wild animals. Recently, several putative pestiviruses species have been discovered and characterized in mammalian species (giraffe pestivirus, antelope pestivirus, HoBi virus,
Gatto IRH, Sonálio K, de Oliveira LG.
europepmc +5 more sources
First detection and genetic characterization of atypical Porcine pestivirus in pigs, Thailand. [PDF]
Atypical Porcine Pestivirus (APPV) is an emerging pathogen in pigs. The virus causes diseases associated with neurological disorders, such as congenital tremors (CT) Type A-II in piglets, leading to economic losses in the swine industry. This study investigated an outbreak of Atypical Porcine Pestivirus (APPV) on a commercial pig farm in eastern of ...
Shahid S +8 more
europepmc +3 more sources
Immunogenicity of subunit vaccine of E2 protein against atypical porcine pestivirus in pigs. [PDF]
Introduction An atypical porcine pestivirus (APPV) causes congenital tremor (CT) type A-II in piglets and has caused considerable financial losses to the pig industry worldwide.
Huang Y +5 more
europepmc +4 more sources
Atypical Porcine Pestivirus Circulation and Molecular Evolution within an Affected Swine Herd. [PDF]
Atypical porcine pestivirus (APPV) is a single-stranded RNA virus from the family Flaviviridae, which is linked to congenital tremor (CT) type A-II in newborn piglets. Here, we retrospectively investigated the molecular evolution of APPV on an affected herd between 2013 and 2019.
Folgueiras-González A +5 more
europepmc +5 more sources
Detection of atypical porcine pestivirus in Swedish piglets with congenital tremor type A-II. [PDF]
Abstract Background Congenital tremor type A-II is a neurological disorder characterized by tremor of the head and body of new-born piglets. The suggestive causative agent of the disease is the recently found atypical porcine pestivirus. The virus has been detected in piglets suffering from congenital tremor in central Europe, South and North ...
Stenberg H, Jacobson M, Malmberg M.
europepmc +6 more sources
Near-Complete Genome Sequence of a Newly Emerging Subgenotype of Atypical Porcine Pestivirus. [PDF]
This study reports the near-complete genome sequence of GD-CT4, a strain of a newly emerging subgenotype of atypical porcine pestivirus detected in a newborn piglet with congenital tremors in Guangdong Province, China. This sequence will improve the understanding of the epidemiology and genetic characteristics of atypical porcine pestivirus.
Wang X, Xie Y, He D, Yan H.
europepmc +3 more sources
Long-Term Circulation of Atypical Porcine Pestivirus (APPV) within Switzerland. [PDF]
In 2015, a new pestivirus was described in pig sera in the United States. This new “atypical porcine pestivirus” (APPV) was later associated with congenital tremor (CT) in newborn piglets. The virus appears to be distributed worldwide, but the limited knowledge of virus diversity and the use of various diagnostic tests prevent direct comparisons ...
Kaufmann C +6 more
europepmc +8 more sources
Pestivirus K (Atypical Porcine Pestivirus): Update on the Virus, Viral Infection, and the Association with Congenital Tremor in Newborn Piglets. [PDF]
The atypical porcine pestivirus (APPV) belongs to the species Pestivirus K of the genus Pestivirus and the family Flaviviridae, and it has been associated with congenital tremor (CT) type A-II in newborn piglets. Although APPV was discovered in 2015, evidence shows that APPV has circulated in pig herds for many years, at least since 1986.
Dall Agnol AM, Alfieri AF, Alfieri AA.
europepmc +5 more sources

