Results 31 to 40 of about 501 (101)

Understanding the global distribution of atypical porcine pestivirus (APPeV)

Animal Health Research Reviews, 2023
AbstractAtypical porcine pestivirus (APPeV) is a pestivirus affecting pigs, notably causing high mortality in piglets due to neurological issues that impair suckling. This study reviews global literature from 2015 to March 2024, assessing APPeV prevalence.
Ugonna Henry Uzoka, Abelardo Silva-Júnior   +1 more
openaire   +2 more sources

Porcine Circovirus Type 3: Diagnostics, Genotyping, and Challenges in Vaccine Development

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Porcine circovirus (PCV) comprises four distinct species, namely, PCV1–4, with considerable differences between them, resulting in limited crossprotection. PCV2 inflicts substantial economic losses on the swine industry. PCV3 was found to have been circulating before its discovery in 2015.
Stella Pranoto, Hsing-Chieh Wu, Chun-Yen Chu, Lin-Zhu Ren   +3 more
wiley   +1 more source

Spatiotemporal analysis of reported classical swine fever outbreaks in China (2005–2018) and the influence of weather

Transboundary and Emerging Diseases, Volume 69, Issue 5, Page e3183-e3195, September 2022., 2022
Abstract Classical swine fever (CSF) is a viral disease that causes enormous economic losses in the swine industry in endemic countries including China. The aims of the current study were to describe the spatial distribution of annual CSF reports in China from 2005 to 2018, identify spatiotemporal clusters of annual CSF reports during this time period ...
Xiao Lu, Michael P. Ward
wiley   +1 more source

Application of shotgun metagenomics sequencing and targeted sequence capture to detect circulating porcine viruses in the Dutch–German border region

Transboundary and Emerging Diseases, Volume 69, Issue 4, Page 2306-2319, July 2022., 2022
Abstract Porcine viruses have been emerging in recent decades, threatening animal and human health, as well as economic stability for pig farmers worldwide. Next‐generation sequencing (NGS) can detect and characterize known and unknown viruses but has limited sensitivity when an unbiased approach, such as shotgun metagenomics sequencing, is used.
Leonard Schuele, Erley Lizarazo‐Forero, Katrin Strutzberg‐Minder, Sabine Schütze, Sandra Löbert, Claudia Lambrecht, Jürgen Harlizius, Alex W. Friedrich, Silke Peter, John W. A. Rossen, Natacha Couto   +10 more
wiley   +1 more source

Investigation into an outbreak of Border disease virus in pigs in England

Transboundary and Emerging Diseases, Volume 69, Issue 4, Page 1698-1706, July 2022., 2022
Abstract Border disease (BD) was first reported in 1959 in lambs from the border region of England and Wales. The causative virus (BD virus; BDV) has since been identified in several other ruminant species and pigs. The virus is prevalent in sheep flocks of UK, Europe and USA and has potential to inflict substantial economic losses.
Akbar Dastjerdi, Rebecca Strong, S. Anna La Rocca, Mark Wessels, Julie Wessels, Kate Whitaker, Ben Strugnell, Susanna Williamson   +7 more
wiley   +1 more source

Chimeric Flaviviral RNA−siRNA Molecules Resist Degradation by The Exoribonuclease Xrn1 and Trigger Gene Silencing in Mammalian Cells

ChemBioChem, Volume 22, Issue 21, Page 3099-3106, November 3, 2021., 2021
Chimeric molecules comprising an Xrn1‐resistant RNA motif (xrRNA) and a small interfering RNA (siRNA) duplex were engineered. The molecules self‐assemble in vitro, resist degradation by the conserved eukaryotic 5’ to 3’ exoribonuclease Xrn1, and trigger gene silencing in mammalian cells.
Cressida Harvey, Sven Klassa, Esteban Finol, Jonathan Hall, Alyssa C. Hill   +4 more
wiley   +1 more source

Porcine circovirus 3 (PCV‐3) as a causal agent of disease in swine and a proposal of PCV‐3 associated disease case definition

Transboundary and Emerging Diseases, Volume 68, Issue 6, Page 2936-2948, November 2021., 2021
Abstract Porcine circovirus 3 (PCV‐3) was discovered in 2015 using next‐generation sequencing (NGS) methods. Since then, the virus has been detected worldwide in pigs displaying several clinical–pathological outcomes as well as in healthy animals. The objective of this review is to critically discuss the evidence existing so far regarding PCV‐3 as a ...
Viviane Saporiti, Giovanni Franzo, Marina Sibila, Joaquim Segalés   +3 more
wiley   +1 more source

Pathology of the outbreak of subgenotype 2.5 classical swine fever virus in northern Vietnam

Veterinary Medicine and Science, Volume 7, Issue 1, Page 164-174, January 2021., 2021
In this study, natural cases of classical swine fever in northern Vietnam showed variable degree of lymphoid depletions in the lymphoid organs including lymph node, tonsil and spleen; with the remaining parenchyma replaced with reticulo‐histiocytic hyperplasia.
Uda Zahli Izzati, Nguyen Thi Hoa, Nguyen Thi Lan, Nguyen Van Diep, Naoyuki Fuke, Takuya Hirai, Ryoji Yamaguchi   +6 more
wiley   +1 more source

An alternative strategy for studying emerging atypical porcine pestivirus [PDF]

Journal of Vaccines and Immunology, 2020
Atypical Porcine Pestivirus (APPV) is an emerging agent that belongs to the genus Pestivirus of the family Flaviviridae and causes Congenital Tremor (CT) in newborn piglets.
Ren Xujiao, Liu Xueyan, Li Jianglong, Chen Huanchun, Li Xiangmin, Qian Ping   +5 more
openaire   +1 more source

Bovine viral diarrhea virus: An updated American College of Veterinary Internal Medicine consensus statement with focus on virus biology, hosts, immunosuppression, and vaccination

Journal of Veterinary Internal Medicine, Volume 34, Issue 5, Page 1690-1706, September 2020., 2020
Abstract Control of bovine viral diarrhea virus (BVDV) in cattle populations across most of the world has remained elusive in spite of advances in knowledge about this viral pathogen. A central feature of virus perseverance in cattle herds is the unique mechanism of persistent infection.
Paul H. Walz, Manuel F. Chamorro, Shollie M. Falkenberg, Thomas Passler, Frank van der Meer, Amelia R. Woolums   +5 more
wiley   +1 more source